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- Clone
- N271/44 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- ACCN2, ASIC, BNaC2, Acid-sensing ion channel 1, degenerin 2, brain sodium channel 2, acid sensing ion channel, amiloride-sensitive cation channel 2, neuronal
- Previously
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Covance Catalog# MMS-5261
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Western blot of anti-ASIC1 antibody (clone N271/44). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain membrane lysate; Lane 3: 20 µg of mouse brain membrane lysate; Lane 4: 20µg of rat brain membrane lysate. The blot was incubated with 10 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat# 405301). Enhanced chemiluminescence was used as the detection system.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 833501 | 100 µL | 165 CHF | ||||
Acid-sensing ion channel (ASIC) 1, also known as brain sodium channel (BNaC2), degenerin 2 and amiloride-sensitive cation channel 2 (ACCN2), is a sodium channel activated by extracellular protons that is expressed in nearly all neurons. ASIC1 may play a role in learning, pain transduction, memory development, and fear conditioning.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
WB
- Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting.
The optimal working dilution should be determined for each specific assay condition.
• WB: 4-10 µg/ml - Application Notes
-
This antibody is effective in immunoblotting (WB).
*Expected MW: 60 kD
WB Positive Control: Human, mouse and rat brain membrane lysates. This clone cross-reacts with human ASIC1, however detection level is weaker than that observed with mouse or rat AISC1. - RRID
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AB_2564967 (BioLegend Cat. No. 833501)
Antigen Details
- Biology Area
- Cell Biology, Neuroscience, Signal Transduction, Synaptic Biology
- Molecular Family
- Postsynaptic proteins, Presynaptic proteins
- Gene ID
- 11419 View all products for this Gene ID
- UniProt
- View information about ASIC1 on UniProt.org
Related FAQs
Other Formats
View All ASIC1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-ASIC1 | N271/44 | WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-ASIC1
Western blot of anti-ASIC1 antibody (clone N271/44). Lane 1:...
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