- Clone
- CON.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Clathrin light chain A, clathrin, light polypeptide (Lca)
- Previously
-
Covance Catalog# MMS-423P
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
811501 | 100 µL | 305 CHF |
Clathrin consists of three heavy chains (192kD). The three light chains (LCa or LCb, 25-29kD) self-assembles into a polyhedral cytoskeletal element. The self-assembly facilitates clathrin's central role in membrane sorting and selective transport within the cell.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was raised against a peptide derived from bovine clathrin light chain corresponding to the conserved region of the light chains, residues 23-44.
- Formulation
- Phosphate-buffered solution + 0.03% Thimerosal.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- Store frozen (-20 or -80°C); shipped on blue ice. Aliquot upon receipt before freezing. Avoid repeated freeze/thaw cycles.
- Application
-
IHC-P - Quality tested
ICC - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10 µg/ml is suggested. For immunocytochemistry, a concentration range of 1.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
-
Application References
(PubMed link indicates BioLegend citation) -
- Zlatic SA, et al. 2013. Mol Biol Cell. 24:2378-88.
- Jiang R, et al. 2000. J Biol Chem. 275(12):8439-47.
- Nathke IS, et al. 1992. Cell. 68:899-910.
- Jackson AP, et al. 1987. Nature. 326:154-9.
- RRID
-
AB_2564758 (BioLegend Cat. No. 811501)
Antigen Details
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
- Gene ID
- 1211 View all products for this Gene ID
- UniProt
- View information about Clathrin Light Chain on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All Clathrin Light Chain (CLTA) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Clathrin Light Chain (CLTA) | CON.1 | IHC-P,ICC |
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