- Clone
- W17128A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- DEPTOR, DEPDC6
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
610201 | 25 µg | 101 CHF | ||||
610202 | 100 µg | 253 CHF |
DEPTOR/DEPDC6, found only in vertebrates, plays an important role in multiple cellular processes such as cell growth, autophagy, apoptosis, ER stress and adipogenesis. It inbibits mTORC1 and mTORC2 kinase activity through direct interaction with mTOR in these complexes. DEPTOR also associates with chromatin and may regulate transcription, and can act as either an oncogene or oncosuppressor depending on cell- or tissue-specific context.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat, Hamster
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant Human DEPTOR Protein (1-219 a.a.)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2783359 (BioLegend Cat. No. 610201)
AB_2783359 (BioLegend Cat. No. 610202)
Antigen Details
- Distribution
-
Cytoplasm/ Nucleus, A little bit more in Cytoplasm
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Chromatin Remodeling/Epigenetics, Signal Transduction, Transcription Factors
- Molecular Family
- Tumor Suppressors
- Gene ID
- 64798 View all products for this Gene ID
- UniProt
- View information about DEPTOR on UniProt.org
Related FAQs
Other Formats
View All DEPTOR Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-DEPTOR | W17128A | WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-DEPTOR
Total cell lysates (15 µg total protein) from A431, NTERA2 (...
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