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- Clone
- W15099A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TNFR-I, TNFRSF1A, P55, P60
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood monocytes were stained with purified anti-human CD120a (clone W15099A) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 369902 | 100 µg | 218 CHF | ||||
CD120a, also known as tumor necrosis factor receptor type 1 (TNF-R1) is 55 kD member of tumor necrosis receptor superfamily (TNFRSF) which which upon binding tumor necrosis factor alpha (TNFα), homotrimerizes to interact death domain of TRADD. CD120a, in association with TRADD, leads to activation of NF-κB signaling, in addition to apoptotic and inflammatory responses.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length human CD120a transfectant cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2650760 (BioLegend Cat. No. 369902)
Antigen Details
- Structure
- 55 kD, single pass type 1 membrane protein, TNFR superfamily.
- Distribution
- Granulocytes, monocytes, and lymphocytes.
- Function
- Homotrimerizes upon binding TNF, activates apoptotic and NFkB signaling.
- Ligand/Receptor
- TNFα, LTα (TNFβ)
- Cell Type
- Granulocytes, Monocytes, Lymphocytes, Neutrophils, Eosinophils
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Loetscher H, et al. 1990. Proc. Natl. Acad. Sci. USA 87:3127.
2. Crowe PD, et al. 1994. J. Immunol. 264:707.
3. Aggarwal BB, et al. 1985. J. Biol. Chem. 260:2345.
4. Chan FK, et al. 2000. Science. 288:2351.
5. Sugano M, et al. 2002. Atherosclerosis 162:77.
6. Cottin V, et al. 2002. J. Immunol. 168:4095.
7. Barnhart BC, Peter ME. 2003. Cell. 114:148. - Gene ID
- 7132 View all products for this Gene ID
- UniProt
- View information about CD120a on UniProt.org
Other Formats
View All CD120a Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD120a | W15099A | FC |
| PE anti-human CD120a | W15099A | FC |
| APC anti-human CD120a | W15099A | FC |
| Biotin anti-human CD120a | W15099A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD120a
Human peripheral blood monocytes were stained with purified ... -
PE anti-human CD120a
Human peripheral blood monocytes were stained with anti-huma... -
APC anti-human CD120a
Human peripheral blood monocytes were stained with anti-huma... -
Biotin anti-human CD120a
Human peripheral blood monocytes were stained with biotinyla...
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