- Clone
- QA20B07 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Macrosialin
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
381202 | 100 µg | 112 CHF |
CD68, also known as macrosialin, is a 110 kD glycoprotein which belongs to the sialomucin family. It is closely related to the family of acidic, highly glycosylated lysosomal-associated membrane proteins (LAMPs). CD68 is predominately expressed in cytoplasmic granules of monocytes/macrophages, dendritic cells, and granulocytes. It is one of the useful myeloid cell markers. Further studies have shown that CD68 is also expressed by a subset of hematopoietic progenitors, γ/δ T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells. The biological function of CD68 is still unknown.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
IHC-F, IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2922613 (BioLegend Cat. No. 381202)
Antigen Details
- Structure
- Sialomucin family, 110 kD
- Distribution
-
Monocytes/macrophages, dendritic cells, granulocytes, subset of hematopoietic progenitors, γ/δ T cells, NK cells, LAK cells, subset of B cells, fibroblasts, endothelial cells
- Molecular Family
- CD Molecules
- Antigen References
-
- Holness CL and Simmons DL. 1993. Blood. 81:1607-13.
- Gottfried E, et al. 2008. Scand J Immunol. 67:453-63.
- Hameed A, et al. 1994. Hum Pathol. 25:872-6.
- Gene ID
- 968 View all products for this Gene ID
- UniProt
- View information about CD68 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD68 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD68 Recombinant Antibody | QA20B07 | IHC-P |
Alexa Fluor® 647 anti-human CD68 Recombinant Antibody | QA20B07 | IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD68 Recombinant Antibody
Human paraffin-embedded tonsil tissue slices were prepared w... -
Alexa Fluor® 647 anti-human CD68 Recombinant Antibody
Human paraffin-embedded tonsil tissue slices were prepared w... Human paraffin-embedded prostate tissue slices were prepared...
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