Purified anti-human FcRL6 Antibody anti-FcRL6

Pricing & Availability

Clone: 7B7/FcRL6 (See other available formats)
Regulatory Status: RUO
Other Names: FcRL6, Fc receptor like 6
Isotype: Mouse IgG1, κ
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Product Citations: publications

7B7slashFcRL6_PURe_FcRL6_Antibody_1_040717 — Human peripheral blood lymphocytes were stained with CD56 Alexa Fluor® 647 and FcRL6 (clone 7B7/FcRL6) Purified (top) or mouse Ig1, κ Purified isotype control (bottom), followed by anti-mouse IgG1 PE.

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373902

100 µg

206 CHF

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Description

FcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8⁺ T cells). Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: BW5147 transduced with HA-tagged FcRL6
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2687026 (BioLegend Cat. No. 373902)

Antigen Details

Structure: Type I transmembrane glycoprotein, Ig gene superfamily
Distribution: NK, T subset
Cell Type: NK cells, T cells
Biology Area: Immunology
Molecular Family: Fc Receptors
Antigen References: 1. Davis RS. 2007. Annu. Rev. Immunol. 25:525.
2. Wilson TJ, et al. 2007. Blood 109:3786.
3. Schreeder DM, et al. 2008. 38:3159.
Gene ID: 343413 View all products for this Gene ID
UniProt: View information about FcRL6 on UniProt.org

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Other Formats

View All FcRL6 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human FcRL6	7B7/FcRL6	FC
APC anti-human FcRL6	7B7/FcRL6	FC
PE anti-human FcRL6	7B7/FcRL6	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 04.10.2017

For Research Use Only. Not for diagnostic or therapeutic use.

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