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Purified anti-human TACSTD2 (TROP2) Antibody

Pricing & Availability
Clone
NY18 (See other available formats)
Regulatory Status
RUO
Other Names
TROP-2, EGP1, Tumor-associated calcium signal transducer 2, GP50, M1S1, EGP-1, GA7331, GA733-1
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
NY18_Purified_TACSTD2_Antibody_FC_100314
Human prostate cancer cell line, PC-3, was stained with purified TACSTD2 (clone NY18, filled histogram) or mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • NY18_Purified_TACSTD2_Antibody_FC_100314
    Human prostate cancer cell line, PC-3, was stained with purified TACSTD2 (clone NY18, filled histogram) or mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
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363801 25 µg 112 CHF
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363802 100 µg 241 CHF
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Description

TACSTD2, also known as TROP-2, is a 35.7 kD protein that belongs to the EpCAM family. It is a cell surface receptor that can transduce calcium signals. Mutations of this gene are associated with gelatinous drop-like corneal dystrophy.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
PK-1 (Human)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2564378 (BioLegend Cat. No. 363801)
AB_2564378 (BioLegend Cat. No. 363802)

Antigen Details

Structure
35.7 kD, EpCAM family member, contains thyroglobulin type-1 domain.
Distribution
Placenta, pancreatic carcinoma cell lines.
Function
Calcium signaling, growth factor receptor.
Cell Type
Embryonic Stem Cells
Biology Area
Immunology, Stem Cells
Antigen References

1. Huang H, et al. 2005. Clin. Cancer Res. 11:4357.
2. Markoff A, et al. 2006. Mol. Vis. 12:1473.
3. Grade M, et al. 2011. Int. J. Cancer 128:1069.
4. Liu T, et al. 2013. PLos One 8:e75864.
5. Lin H, et al. 2014. Int. J. Cancer 134:1239.
6. Yang J, et al. 2013. Int. J. Oncol. 43:859.

Gene ID
4070 View all products for this Gene ID
UniProt
View information about TACSTD2 on UniProt.org
Go To Top Version: 1    Revision Date: 11.03.2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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