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Purified anti-mouse CD129 (IL-9R) Antibody

Pricing & Availability
Clone
S18011D (See other available formats)
Regulatory Status
RUO
Other Names
Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9Rα
Isotype
Rat IgG1, κ
Ave. Rating
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Product Citations
publications
S18011D_PURE_CD129_Antibody_031720
C57BL/6 mouse splenocytes were cultured with anti-mouse CD40 antibody for four days. Cells were stained with purified CD129 (clone S18011D) (left) or purified rat IgG1, κ isotype (right), followed by anti-rat IgG APC and CD19 PE.
  • S18011D_PURE_CD129_Antibody_031720
    C57BL/6 mouse splenocytes were cultured with anti-mouse CD40 antibody for four days. Cells were stained with purified CD129 (clone S18011D) (left) or purified rat IgG1, κ isotype (right), followed by anti-rat IgG APC and CD19 PE.
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158802 500 µg 581 CHF
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Description

CD129 is the ligand binding subunit of IL-9 receptor (IL-9R or IL-9Rα). It is a type I transmembrance glycoprotein belonging to the hematopoientin receptor superfamily. The signal transducing subunit is common gamma chain (γc, CD132), which is shared with receptors for IL-2, IL-4, IL-7, and IL-21. The mouse IL-9R has 468aa and is about 52.2 kD. Besides modulating immune response, signals through IL-9 and IL-9R are also invoved in allergy and inflammatory disorders.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse IL-9R transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1.  Pajulas, A. et al. 2023. Mucosal Immunology. 16(4), 432-445. PubMed
RRID
AB_2832565 (BioLegend Cat. No. 158802)

Antigen Details

Structure
Type I transmemberane glycoprotein; WSXWS motif
Distribution

Subset of B cells, mast cells

Function
Binding IL-9; activate JAK-STAT signaling
Interaction
Common gamma chain (CD132)
Ligand/Receptor
IL-9
Cell Type
B cells, Eosinophils, Mast cells, T cells, Thymocytes
Biology Area
Adaptive Immunity, Immuno-Oncology, Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, Growth Factors
Antigen References
  1. Druez C, et al. 1990. J Immunol. 145:2494-9.
  2. Renauld JC, et al. 1992. Proc Natl Acad Sci USA. 89:5690.
  3. Takatsuka S, et al. 2018. Nat Immunol. 19:1025-34.
Gene ID
16199 View all products for this Gene ID
UniProt
View information about CD129 on UniProt.org
Go To Top Version: 1    Revision Date: 03.17.2020

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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