- Clone
- M380B (See other available formats)
- Regulatory Status
- RUO
- Isotype
- Mouse IgG1
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
944101 | 25 µg | 118 CHF | ||||
944102 | 100 µg | 293 CHF |
Phosphorylation of specific serine residues is a post-translational modification event critical for regulating the activity of many proteins. Protein phosphorylation events can alter protein function through a variety of molecular mechanisms, ranging from conformational changes that can stimulate or inhibit protein function to facilitating protein-protein interactions with binding partners. Antibodies that can detect phosphoserine residues are valuable tools for identifying novel phospho-sites and characterizing changes in the post-translational state of a broad range of phosphorylated proteins.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat, All Species
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Synthetic peptide containing phosphorylated serine
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC, IP, ICFC - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1.0 µg/mL. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/mL is recommended. For immunoprecipitation, the suggested use of this reagent is 2.5 µg/test. For flow cytometric staining using our True-Phos™ Perm Buffer, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2890869 (BioLegend Cat. No. 944101)
AB_2890869 (BioLegend Cat. No. 944102)
Antigen Details
- Function
- Cell signaling
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Molecular Family
- Phospho-Proteins, Protein Kinases/Phosphatase
- Antigen References
-
1. Rogerson D. et. al. 2015. Nat. Chem. Biol. 11:496-503.
2. Steinfield J. et. al. 2014. ACS Chem. Biol. 9(5):1104-1112. - Gene ID
- NA
- UniProt
- View information about Phosphoserine on UniProt.org
Other Formats
View All Phosphoserine Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Phosphoserine | M380B | WB,ICC,IP,ICFC |
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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