- Clone
- TX24 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Poliovirus receptor (PVR), nectin-like 5
- Isotype
- Mouse IgG2a, λ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
337502 | 100 µg | 229 CHF |
CD155, known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. It is a nectin-like molecule belonging to Ig superfamily. CD155 is primarily found on endothelial cells, monocytes, epithelia and central nervous system. CD155 is an adhesion molecule involved in cell-cell and cell-matrix adhesion through interaction with CD226, CD96 (Tactile), nectin-1, -2, and -3 (CD111, CD112, CD113), and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications include: partially inhibits NK- and T-cell mediated cytotoxicity
-
Application References
(PubMed link indicates BioLegend citation) -
- Tahara-Hanaoka S, et al. 2004. Intl. Immunol. 16:533
- RRID
-
AB_1279096 (BioLegend Cat. No. 337502)
Antigen Details
- Structure
- Type I glycoprotein, Ig superfamily
- Distribution
-
Monocytes, endothelial cells, epithelia, central nervous system
- Ligand/Receptor
- CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus
- Cell Type
- Monocytes, Endothelial cells, Epithelial cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication
2. Fuchs A, et al. 2004. J. Immunol. 172:3994
3. Bottino PD, et al. 2005. Mol. Immunol. 42:463 - Gene ID
- 5817 View all products for this Gene ID
- UniProt
- View information about CD155 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD155 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD155 (PVR) | TX24 | FC |
PE anti-human CD155 (PVR) | TX24 | FC |
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