Loading...

Purified anti-mouse CD3ε Antibody

Pricing & Availability
Clone
145-2C11 (See other available formats)
Regulatory Status
RUO
Other Names
CD3ε, T3, CD3
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
145-2C11_Pure_021606
C57BL/6 mouse splenocytes were stained with purified CD3e (clone 145-2C11) (filled histogram) or Armenian hamster IgG isotype control (open histogram), followed by anti-Armenian hamster IgG FITC.
  • 145-2C11_Pure_021606
    C57BL/6 mouse splenocytes were stained with purified CD3e (clone 145-2C11) (filled histogram) or Armenian hamster IgG isotype control (open histogram), followed by anti-Armenian hamster IgG FITC.
  • 145-2C11_PURE_CD3e_Antibody_IHC-F_033017
    C57BL/6 mouse frozen spleen section was fixed with 4% paraformaldehyde (PFA) for ten minutes at room temperature and blocked with 5% FBS for 30 minutes at room temperature. Then the section was stained with 10 µg/mL of purified anti-mouse CD3ε (clone 145-2C11) and 10 µg/mL of Alexa Fluor® 488 anti-mouse/human CD45R/B220 (clone RA3-6B2) (green) overnight at 4°C, followed by 2.5 µg/mL of Alexa Fluor® 594 Goat anti-hamster (Armenian) IgG (clone Poly4055) (red) for two hours at room temperature. The image was captured by 10X objective.
  • 145-2C11_PURE_CD3e_Antibody_IHC-F_2_102518
    Fresh, frozen mouse spleen was stained with purified CD3ε clone 145-2C11 conjugated and detected with a Cy3 CODEX™ oligonucleotide duplex (red). Samples were counterstained with B220 A647 (green). Data generated at Akoya Biosciences, Inc. using the CODEX™ technology.
Compare all formats
Cat # Size Price Quantity Check Availability Save
100301 50 µg 24 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
100302 500 µg 72 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD3ε antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
IP, Activ, Block, WB, ICC - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. For immunohistochemical staining on frozen tissue sections, the suggested use of this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 145-2C11 is useful for in vitro blocking of target-specific CTL-mediated cell lysis1, as well as T cell activation assays, inducing proliferation and cytokine production1,2,7,12,16. It also induces apoptosis in immature thymocytes32,  and in vivo T cell depletion8-10. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1, immunohistochemical staining14,15 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, Western blotting4, complement-mediated cytotoxicity6, in vitro and in vivo stimulation of T cells1,2,7,12,16, immunofluorescent staining5, and in vivo T cell depletion8-10. The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells11. Clone 145-2C11 is not recommended for formalin-fixed paraffin embedded sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 100314). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100340) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).

Application References

(PubMed link indicates BioLegend citation)
  1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activ, Block)
  2. Kruisbeek AM, et al. 1991. In Current Protocols in Immunology. 3.12.1. (Activ)
  3. Duke RC, et al. 1995. Current Protocols in Immunology. 3.17.1.
  4. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  5. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  6. Jacobs H, et al. 1994. Eur. J. Immunol. 24:934. (CMCD)
  7. Vossen ACTM, et al. 1995. Eur. J. Immunol. 25:1492. (Activ)
  8. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  9. Kinnaert P, et al. 1996. Transpl. Int. 9:386. (Deplete)
  10. Han WR, et al. 1999. Transpl. Immunol. 7:207. (Deplete)
  11. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  12. Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Activ)
  13. Ko SY, et al. 2005. J. Immunol. 175:3309.
  14. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC-F)
  15. Tilley SL, et al. 2007. J. Immunol. 178:3208. (IHC-F)
  16. Wang W, et al. 2007. J. Immunol. 178:4885. (Activ)
  17. Xiao S, et al. 2007. J. Exp. Med. 204:1691.
  18. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed.
  19. Curtsinger JM, et al.2005. J. Immunol. 175:4392. PubMed
  20. Guo Y, et al. 2008. Blood 112:480. PubMed
  21. Kenna TJ, et al. 2008. Blood 111:2091.
  22. Perchonock CE, et al. 2007. J. Immunol. 179:1768. PubMed
  23. Perchonock GE, et al. 2006. Mol. Cell. Biol. 26:6005. PubMed
  24. Kanaya T, et al. 2008. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G273. PubMed
  25. de Koning BA, et al. 2006. Int. Immunol. 18:941. PubMed
  26. Schulteis RD, et al. 2008. Blood 295:G273. PubMed
  27. Qi Q, et al. 2009. Blood 114:564. PubMed
  28. Helmersson S, et al. 2013. Am J Pathol. 9440:123. Pubmed
  29. Wu S, et al. 2014. Clin Vaccine Immunol. 21:156. PubMed
  30. Yan J, et al. 2014. Vaccine. 32:2833. PubMed
  31. Guiterrez DA, et al. 2014. Diaebetes. 63:3827. PubMed
  32. Shi YF, et al. 1991. J Immunol. 146:3340. (Apop)
Product Citations
  1. Kim K, et al. 2016. PLoS One. 11: 0148576. PubMed
  2. Sandu I, et al. 2020. Nat Commun. 11:4454. PubMed
  3. Kobayashi A, et al. 2021. Front Immunol. 12:650856. PubMed
  4. Paterson MJ, et al. 2020. PLoS Pathog. 16:e1008733. PubMed
  5. Tian J, et al. 2021. Autophagy. 17:2586. PubMed
  6. Tersteegen A, et al. 2021. Infect Immun. 89:. PubMed
  7. Liu CJ, et al. 2020. Neuro Oncol. 22:1276. PubMed
  8. Collin R, et al. 2020. J Immunol. 205:133. PubMed
  9. Malinczak CA, et al. 2021. J Immunol. 206:1315. PubMed
  10. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  11. Koenig A, et al. 2022. Front Immunol. 12:791100. PubMed
  12. Zhu M, et al. 2022. Front Immunol. 13:1019248. PubMed
  13. Briukhovetska D, et al. 2023. Immunity. 56:143. PubMed
  14. Zhang J, et al. 2023. Int J Nanomedicine. 18:209. PubMed
  15. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  16. Schick J, et al. 2023. Elife. 12: . PubMed
  17. Shirai T, et al. 2022. Cancer Sci. 113:3710. PubMed
  18. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  19. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  20. Akiyama C, et al. 2019. J Immunol. 203:835. PubMed
  21. Bergfeld A, et al. 2017. Front Microbiol. 0.919444444. PubMed
  22. Chemnitz J, et al. 2019. Sci Rep. 3.745138889. PubMed
  23. Arnold IC, et al. 2019. PLoS Pathog. 15:e1007866. PubMed
  24. Wolf Y, et al. 2017. J Exp Med. 214:905. PubMed
  25. Boyd DF, et al. 2020. Nature. 587:466. PubMed
  26. Kondo H, et al. 2020. J Biol Chem. 295:1658. PubMed
  27. Wan Mohd Zawawi WFA, et al. 2021. Sci Rep. 11:10278. PubMed
  28. Krovi SH, et al. 2019. Proc Natl Acad Sci U S A. 116:22252. PubMed
  29. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  30. Chartrand K, et al. 2018. Front Immunol. 1.642361111. PubMed
  31. Namavari A, et al. 2012. Invest Ophthalmol Vis Sci . 53:4575. PubMed
  32. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  33. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  34. Goel S, et al. 2017. Nature. 548:471. PubMed
  35. Field CS, et al. 2018. Oncoimmunology. 7:e1376154. PubMed
  36. McLane LM, et al. 2021. Cell Reports. 35(6):109120. PubMed
  37. Liang W, et al. 2022. Methods Mol Biol. 2574:221. PubMed
  38. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  39. Chen L, et al. 2019. Nat Commun. 3.553472222. PubMed
  40. Sanctuary MR, et al. 2019. Mucosal Immunol. 0.638888889. PubMed
  41. Carpenter SM, et al. 2017. PLoS Pathog. 13:e1006704. PubMed
  42. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  43. Crawford G, et al. 2018. Nat Immunol. 1.388194444. PubMed
  44. Cao Q, et al. 2018. Am J Physiol Renal Physiol. 314:F561. PubMed
  45. Oghumu S, et al. 2019. J Immunol. 203:789. PubMed
  46. Jennings EK, et al. 2021. STAR Protocols. 2(1):100284. PubMed
  47. Lu SX, et al. 2021. Cell. . PubMed
  48. Liu W, et al. 2021. Stem Cell Res Ther. 12:153. PubMed
  49. Joseph R, et al. 2021. Br J Cancer. 125:176. PubMed
  50. Willimsky G, et al. 2021. Elife. 10:. PubMed
  51. Quintana E, et al. 2020. Cancer Res. 80:2889. PubMed
  52. Arimura K, et al. 2017. Mucosal Immunol. 1.08125. PubMed
  53. Zhou AC, et al. 2017. Front Immunol. 1.136111111. PubMed
  54. Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed
  55. Muhammad F, et al. 2020. Front Immunol. 975:11. PubMed
  56. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  57. Delgobo M, et al. 2021. Front Immunol. 12:584538. PubMed
  58. Peng V, et al. 2020. J Biol Chem. 295:14866. PubMed
  59. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  60. Edenborough KM, et al. 2019. Front Immunol. 10:2414. PubMed
  61. McLeod RL, et al. 2018. Oncotarget. 9:34459. PubMed
  62. Robert S, et al. 2018. Bone Marrow Transplant. 53:807. PubMed
  63. Morabito KM, et al. 2017. Mucosal Immunol. 0.795138889. PubMed
  64. Rissiek B, et al. 2017. Sci Rep. . 10.1038/s41598-017-16613-w. PubMed
  65. El Maï M, et al. 2021. Cancers (Basel). 13:. PubMed
  66. Baluk P, et al. 2020. Am J Pathol. 190:2355. PubMed
  67. Mullins GN, et al. 2020. Sci Rep. 10:21994. PubMed
  68. Hilligan KL, et al. 2020. Nat Commun. 11:5637. PubMed
  69. Suzuki Y, et al. 2021. FEBS Open Bio. 11:2619. PubMed
  70. Sekiya T et al. 2018. Cell reports. 24(6):1627-1638 . PubMed
  71. Lyon de Ana C, et al. 2019. J Immunol. 202:1112. PubMed
  72. Wu P et al. 2019. Molecular cell. 73(5):1015-1027 . PubMed
  73. Tuzlak S, et al. 2017. Cell Death Differ. 24:523. PubMed
  74. Doorduijn EM, et al. 2018. Front Immunol. 0.416666667. PubMed
  75. Rao TN, et al. 2020. J Immunol. 204:2600. PubMed
  76. Perchonock C, et al. 2006. Mol Cell Biol . 26:6005. PubMed
  77. Guo Y, et al. 2008. Blood. 112:480. PubMed
  78. Zhang P, et al. 2022. BMC Med. 20:435. PubMed
  79. Hanoteau A, et al. 2019. J Immunother Cancer. 7:10. PubMed
  80. Stacey MA, et al. 2017. J Clin Invest. 127:1463. PubMed
  81. Duc D et al. 2019. Cell Rep. 29(2):378-390 . PubMed
  82. Xu L et al. 2017. Immunity. 47(3):538-551 . PubMed
  83. McCully M, et al. 2015. J Immunol. 195: 96 - 104. PubMed
  84. Bremser A, et al. 2015. PLoS One. 10: 0137393. PubMed
  85. Cain MP, et al. 2020. Dis Model Mech. 13:00. PubMed
  86. Takushi SE, et al. 2020. Hum Gene Ther. 31:626. PubMed
  87. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  88. Xie D, et al. 2020. Eur J Immunol. 50:1729. PubMed
  89. Reed J, et al. 2020. Bio Protoc. 10:e3607. PubMed
  90. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  91. Brown IK, et al. 2021. PLoS Pathog. 17:e1009602. PubMed
  92. Chen Z et al. 2019. Immunity. 51(5):840-855 . PubMed
  93. Gartlan KH, et al. 2019. Blood Adv. 2.110416667. PubMed
  94. Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
  95. Di Martino L, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:901. PubMed
  96. James OJ, et al. 2021. Nat Commun. 12:4290. PubMed
  97. Borges TJ, et al. 2018. Nat Commun. 9:3482. PubMed
  98. Hsieh WC, et al. 2020. JCI Insight. 5:00. PubMed
  99. Sharma M, et al. 2020. Circ Res. 127:335. PubMed
  100. Sun L, et al. 2022. Front Immunol. 13:823853. PubMed
  101. Wu G, et al. 2022. Wellcome Open Res. 6:134. PubMed
  102. Otsuka S, et al. 2021. J Clin Invest. 131:. PubMed
  103. Schuler CF, et al. 2020. Allergy. 75:2279. PubMed
  104. Yoon S, et al. 2020. Antioxidants (Basel). 10:. PubMed
  105. Tao H, et al. 2021. Front Immunol. 12:623280. PubMed
  106. Won HY, et al. 2017. Sci Rep. 7:16946. PubMed
  107. Van De Velde LA, et al. 2017. J Biol Chem. 292:15:00. PubMed
  108. Scholz T, et al. 2017. PLoS One. 12:e0182646. PubMed
  109. Sprouse ML, et al. 2018. JCI Insight. 3:e97322. PubMed
  110. Lee JY, et al. 2018. Front Immunol. 0.678472222. PubMed
  111. Sharabi A, et al. 2019. JCI Insight. 4:e126294. PubMed
  112. Du J, et al. 2018. AMB Express. 8:158. PubMed
  113. Majer O, et al. 2019. Nature. 575:366. PubMed
  114. Ma VP, et al. 2022. Sci Adv. 8:eabg4485. PubMed
  115. Li Z, et al. 2021. MBio. 12:e0254221. PubMed
  116. Ejima R, et al. 2021. Nutrients. 13:. PubMed
  117. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  118. Chen HW, et al. 2021. Biomedicines. 9:. PubMed
  119. Seo N, et al. 2018. Nat Commun. 9:435. PubMed
  120. Parzmair GP, et al. 2017. J Leukoc Biol. 101:407. PubMed
  121. Kälin S et al. 2017. Cell metabolism. 26(3):475-492 . PubMed
  122. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  123. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  124. Hao Y, et al. 2018. Front Immunol. 9:1127. PubMed
  125. Sandy A, et al. 2013. J Immunol. 190:5818. PubMed
  126. Sripada A, et al. 2021. PLoS Biol. 19:e3001063. PubMed
  127. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  128. Wu Y, et al. 2021. J Clin Invest. 131:. PubMed
  129. Rigo MM, et al. 2020. FEBS J. :. PubMed
  130. Baluk P, et al. 2018. Methods Mol Biol. 1846:161. PubMed
  131. Katagiri T, et al. 2019. Mucosal Immunol. 12:p1104. PubMed
  132. Wang HC, et al. 2017. J Immunol. 198:3149. PubMed
  133. Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed
  134. Klein JC, et al. 2017. Nat Commun. 8:14600. PubMed
  135. Goh W, et al. 2020. Cell Rep. 33:108285. PubMed
  136. Lee J, et al. 2020. Cells. 9:. PubMed
  137. Seo SU, et al. 2021. Front Immunol. 12:697162. PubMed
  138. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  139. Wang W, et al. 2018. J Vasc Surg. 68:1538. PubMed
  140. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  141. Fernández-Orth J, et al. 2020. Eur J Immunol. . PubMed
  142. Aguilar OA, et al. 2020. J Immunol. 205:1709. PubMed
  143. Taylor MD, et al. 2020. Front Immunol. 11:1946. PubMed
  144. Kissiov DU, et al. 2022. Elife. 11:. PubMed
  145. Yoon S, et al. 2022. Nat Commun. 13:1602. PubMed
  146. Link MA, et al. 2017. PLoS One. 12:e0184320. PubMed
  147. Teijeira A, et al. 2018. Cancer Immunol Res. 6:798. PubMed
  148. Jiao S, et al. 2020. Cell. 179(5):1177-1190.e13.. PubMed
  149. Chen Z, et al. 2021. Cell. 184(5):1262-1280.e22. PubMed
  150. Gaspar M, et al. 2020. Cancer Immunol Res. 0.875694444. PubMed
  151. Koch K, et al. 2022. Int J Mol Sci. 23:. PubMed
  152. Yang H, et al. 2022. Cell Death Discov. 8:183. PubMed
  153. Qiu Z, et al. 2022. Cancer Discov. 12:502. PubMed
  154. Sun Y, et al. 2021. Nat Commun. 12:5147. PubMed
  155. Lin Z, et al. 2021. Stem Cells. 39:240. PubMed
  156. Wagner AK, et al. 2017. Nat Commun. 8:15627. PubMed
  157. Stelekati E, et al. 2018. Cell Rep. 2.445833333. PubMed
  158. Cui X, et al. 2017. J Immunol. 199:4066. PubMed
  159. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  160. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  161. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  162. Dey P, et al. 2020. Cancer Discov. 10:608. PubMed
  163. Schnoegl D, et al. 2022. Front Immunol. 13:909270. PubMed
  164. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  165. Afzali B, et al. 2017. Nat Immunol. 18:813. PubMed
  166. Cohen MA, et al. 2020. Cell Stem Cell. 26(4):579-592. PubMed
  167. Genoud V, et al. 2018. Oncoimmunology. 7:e1501137. PubMed
  168. Taylor MD, et al. 2020. Front Immunol. 11:563402. PubMed
  169. Nagatake T, et al. 2021. Int Immunol. 33:171. PubMed
  170. Sasai M, et al. 2021. J Exp Med. 218:. PubMed
  171. Perchonock C, et al. 2007. J Immunol. 179:1768. PubMed
  172. Cole C, et al. 2018. Nucleic Acids Res. 46:e62. PubMed
  173. Abe Y, et al. 2017. Biochem Biophys Rep. 0.543055556. PubMed
  174. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  175. Lin J, et al. 2017. Nat Commun. . 10.1038/s41467-017-01477-5. PubMed
  176. Wang G, et al. 2015. PLoS One. 10:121968. PubMed
  177. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  178. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  179. Kästle M, et al. 2020. Cell Commun Signal. 183:18. PubMed
  180. Bordoloi D, et al. 2021. Genes Cancer. 12:51. PubMed
  181. Wang W, et al. 2022. Nat Commun. 13:4495. PubMed
  182. An Y et al. 2018. Cell reports. 25(3):702-714 . PubMed
  183. Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed
  184. Akkaya B, et al. 2018. J Immunol. 201:3294. PubMed
  185. Khameneh HJ, et al. 2017. J Immunol. 198:196. PubMed
  186. Wang N, et al. 2020. Front Immunol. 1.765972222. PubMed
  187. Galeano Nio JL, et al. 2020. eLife. 9:00. PubMed
  188. Umeda M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  189. Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
  190. Yamazaki K, et al. 2022. Sci Rep. 12:3242. PubMed
  191. Chen YH, et al. 2022. Arthritis Res Ther. 24:27. PubMed
  192. Sutiwisesak R, et al. 2020. PLoS Pathog. 16:e1009000. PubMed
  193. Xia L, et al. 2021. Cancer Immunol Res. 9:707. PubMed
  194. Fritz Y, et al. 2017. J Invest Dermatol. 137:696. PubMed
RRID
AB_312666 (BioLegend Cat. No. 100301)
AB_312666 (BioLegend Cat. No. 100302)

Antigen Details

Structure
Ig superfamily, forms CD3/TCR complex with CD3δ, γ and ζ subunits and TCR (α/β and γ/δ), 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
TCR signal transduction, T cell activation, antigen recognition
Ligand/Receptor
Peptide antigen/MHC-complex
Cell Type
NKT cells, T cells, Thymocytes, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, TCRs
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12501 View all products for this Gene ID
UniProt
View information about CD3epsilon on UniProt.org
Go To Top Version: 2    Revision Date: 10.17.2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account