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Purified anti-human CD200R Antibody

Pricing & Availability
Clone
OX-108 (See other available formats)
Regulatory Status
RUO
Other Names
CD200R1, MOX2R, Orexin Receptor 2 (OX2R), CD200 Receptor
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
OX-108_Purified_CD200R_Antibody_031219.png
Human peripheral blood lymphocytes were stained with CD200R (clone OX-108) Purified (filled histogram) or Mouse IgG1, κ isotype control (open histogram) followed by Biotin anti-Mouse IgG and Streptavidin-PE.
  • OX-108_Purified_CD200R_Antibody_031219.png
    Human peripheral blood lymphocytes were stained with CD200R (clone OX-108) Purified (filled histogram) or Mouse IgG1, κ isotype control (open histogram) followed by Biotin anti-Mouse IgG and Streptavidin-PE.
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329302 100 µg 95€
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Description

CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils, but also by other leukocytes including T cells and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissues.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CD200R full length fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
ICC - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Wright GJ, et al. 2003. J. Immunol. 171:3034.
Product Citations
  1. Ruetsche D, et al. 2022. Cells. 11:. PubMed
  2. Bengsch B et al. 2018. Immunity. 48(5):1029-1045 . PubMed
RRID
AB_1027731 (BioLegend Cat. No. 329302)

Antigen Details

Structure
Immunoglobulin superfamily glycoprotein.
Distribution

Monocytes, neutrophils, T cells, mast cells.

Ligand/Receptor
CD200, OX2.
Cell Type
Mast cells, Monocytes, Neutrophils, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Wright GJ, et al. 2003. J. Immunol. 171:3034.
2. Gorczynski R, et al. 2004. J. Immunol. 172:7744.

Gene ID
131450 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD200R
Specificity Alt (DOES NOT SHOW ON TDS):
CD200R
App Abbreviation (DOES NOT SHOW ON TDS):
FC,ICC
UniProt
View information about CD200R on UniProt.org
Go To Top Version: 3    Revision Date: 08/09/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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