- Clone
- SHM38 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD213a2, IL-13RA2, IL-13R, IL13BP, CT19
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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354403 | 25 tests | 123€ | ||||
354404 | 100 tests | 288€ |
CD213a2, also known as IL-13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13Ra2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Melanoma cell line A375
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Takenouchi M, et al. 2011. Clin. Cancer Res. 17:2819. (FC)
- Product Citations
-
- RRID
-
AB_11218789 (BioLegend Cat. No. 354403)
AB_11218789 (BioLegend Cat. No. 354404)
Antigen Details
- Structure
- Member of the hematopoietin family, type I transmembrane protein, contains 1 fibronectin type III domain
- Distribution
-
Fibroblasts, smooth muscle cells, keratinocytes, activated B cells
- Function
- Possible decoy receptor, antagonist of CD213a1, internalization of IL-13
- Ligand/Receptor
- IL-13
- Cell Type
- B cells, Fibroblasts
- Biology Area
- Cell Biology, Immunology, Transcription Factors
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Mitchell J, et al. 2010. Curr. Opin. Investig Drugs. 11:527.
2. Strober W, et al. 2009. Curr. Mol. Med. 9:740.
3. Tabata Y, et al. 2007. Curr. Allergy Asthma Rep. 7:338. - Gene ID
- 3598 View all products for this Gene ID
- UniProt
- View information about CD213a2 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD213a2 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD213a2 (IL13Rα2) | SHM38 | FC |
Purified anti-human CD213a2 (IL13Rα2) | SHM38 | FC |
APC anti-human CD213a2 (IL13Rα2) | SHM38 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-human CD213a2 (IL13Rα2)
Human melanoma cell line, A375, was stained with CD213a2 (cl... -
Purified anti-human CD213a2 (IL13Rα2)
Human melanoma cell line, A375, was stained with purified CD... -
APC anti-human CD213a2 (IL13Rα2)
Human melanoma cell line, A375, was stained with CD213a2 (cl...
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