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PE anti-human CD79b (Igβ) Antibody

Pricing & Availability
Clone
CB3-1 (See other available formats)
Regulatory Status
RUO
Workshop
VI CD79.1
Other Names
Igb, Igβ (Ig-beta), B29
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
CB3-1_PE_050109.jpg
Human peripheral blood lymphocytes stained with CB3-1 PE and CD19 (HIB19) APC
  • CB3-1_PE_050109.jpg
    Human peripheral blood lymphocytes stained with CB3-1 PE and CD19 (HIB19) APC
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341404 100 tests 177€
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Description

CD79 is a heterodimeric molecule comprised of an α-chain (CD79a) and β-chain (CD79b). A 37-39 kD type I integral membrane protein CD79b is non-covalently associated with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b is expressed on the surface of surface Ig (sIg)-positive B cells and in the cytoplasm of sIg-negative B cells. It is essential for signal transduction after surface Ig crosslinking.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Nakamura T, et al. 1992. P. Natl. Acad. Sci. USA 89:8522.
  2. Garcia Vela J, et al. 1999. Leukemia. 13:1501.
  3. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  4. Rossi EA, et al. 2014. PLoS One. 9:98315. PubMed
Product Citations
  1. Pape KA, et al. 2021. Cell Rep. 37:109823. PubMed
  2. Frensch M, et al. 2021. Cell Mol Life Sci. 78:8165. PubMed
  3. Pape KA, et al. 2022. JCI Insight. 7:. PubMed
  4. Choi J, et al. 2020. Proc Natl Acad Sci U S A. 117:6092. PubMed
  5. Rossi E, et al. 2014. PLoS One. 9:98315. PubMed
RRID
AB_1595454 (BioLegend Cat. No. 341404)

Antigen Details

Structure
37-39 kD type I integral membrane protein, associate with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex, Ig superfamily.
Distribution

B cells

Function
From BCR complex, signal transduction
Cell Type
B cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc.
2. Dylke J, et al. 2007. Immunol. Lett. 112:47

Gene ID
974 View all products for this Gene ID
UniProt
View information about CD79b on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 08/25/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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