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- Clone
- TX69 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- LMIR4
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Mouse MAIR-IV transfected cells stained with TX-69 PE
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 139605 | 25 µg | 117€ | ||||
MAIR-IV, also known as LMIR4 or CLM5, is a member of the myeloid-associated immunoglobulin-like receptor family (MAIR, CD300). It is preferentially expressed on Gr-1+/Mac-1+ neutrophils in the peripheral blood, bone marrow, peritoneal cavity, and spleen. It is also found on Mac-1+/Gr-1+ macrophages and CD11c+ dendritic cells. In association with the immunoreceptor tyrosine based activating motif (ITAM)-bearing adaptor FcRγ, MAIR-IV mediates activation signals for neutrophils.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- MAIR-IV transfected BW5147 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Additional reported applications (for the relevant formats) include: Western blot1, plate-coated TX69 induced secretion of IL-6, and TNF-α by neutrophils1.
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Application References
(PubMed link indicates BioLegend citation) -
- Nakano T, et al. 2008. Mol. Immunol. 45:289. (Activ, WB)
- Product Citations
-
- RRID
-
AB_10641143 (BioLegend Cat. No. 139605)
Antigen Details
- Structure
- Ig superfamily, associates with ITAM-bearing adaptor FcRγ
- Distribution
- Neutrophils, macrophages, dendritic cells
- Function
- Activates neutrophils
- Cell Type
- Neutrophils, Macrophages, Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Shibuya A, et al. 2009. Immune Network 9:41.
2. Can I, et al. 2008. J. Immunol. 180:207.
3. Nakano T, et al. 2008. Mol. Immunol. 45:289. - Gene ID
- 217305 View all products for this Gene ID
- UniProt
- View information about MAIR-IV on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All MAIR-IV Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-mouse MAIR-IV (CLM-5) | TX69 | FC |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-mouse MAIR-IV (CLM-5)
Mouse MAIR-IV transfected cells stained with TX-69 PE
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