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PE/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-F11_PECy7_090507
C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
  • 30-F11_PECy7_090507
    C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
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103113 25 µg 70€
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103114 100 µg 152€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  2. Garber C, et al. 2019. Nat Neurosci. 1.802777778. PubMed
  3. Dobie R, et al. 2020. Cell Reports. 29(7):1832-1847.e8.. PubMed
  4. Wu JH, et al. 2020. EMBO Mol Med. 12:e10154. PubMed
  5. Rodriguez de la Fuente L, et al. 2021. STAR Protoc. 2:100841. PubMed
  6. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  7. Schädlich IS, et al. 2022. iScience. 25:104470. PubMed
  8. Yang AC, et al. 2020. Nature. 583:425. PubMed
  9. Chen G, et al. 2021. J Mol Cell Cardiol. 159:62. PubMed
  10. Kfoury YS, et al. 2021. Cell Stem Cell. 28:2090. PubMed
  11. He D, et al. 2022. Immunity. 55:159. PubMed
  12. Tapanes S, et al. 2022. Glia. 70:1133. PubMed
  13. Kenney DJ, et al. 2022. Cell Rep. 39:110714. PubMed
  14. Jeong GU, et al. 2022. Microbiol Spectr. 10:e0109122. PubMed
  15. Kiani Shabestari S, et al. 2022. Cell Rep. 39:110961. PubMed
  16. Dong H, et al. 2022. Proc Natl Acad Sci U S A. 119:e2123247119. PubMed
  17. Steudler J, et al. 2022. Glia. 70:2045. PubMed
  18. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  19. Koizumi M, et al. 2022. J Biol Chem. 298:102506. PubMed
  20. Xuan FL, et al. 2022. Front Immunol. 13:1005067. PubMed
  21. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  22. Moiseeva V, et al. 2023. Nature. 613:169. PubMed
  23. An X, et al. 2023. Am J Reprod Immunol. 89:e13676. PubMed
  24. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  25. Taniguchi S, et al. 2023. Nat Commun. 14:143. PubMed
  26. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  27. Hattori Y, et al. 2023. Cell Rep. 42:112092. PubMed
  28. Ismailova A, et al. 2023. Front Immunol. 14:1123344. PubMed
  29. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  30. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  31. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  32. Narvaez del Pilar O, et al. 2022. Development. 149:. PubMed
  33. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  34. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  35. Khare A, et al. 2016. Cell Rep. 15: 1700-1714. PubMed
  36. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  37. Hernandez BJ, et al. 2022. Am J Respir Cell Mol Biol. 67:389. PubMed
  38. Meyer T, et al. 2022. Proc Natl Acad Sci U S A. 119:e2211310119. PubMed
  39. Hong X, et al. 2022. Cell Stem Cell. 29:1298. PubMed
  40. Cronin SJF, et al. 2022. Sci Transl Med. 14:eabj1531. PubMed
  41. Mohamed GA, et al. 2023. Breast Cancer Res. 25:23. PubMed
  42. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  43. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  44. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  45. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  46. Tan X, et al. 2023. Adv Sci (Weinh). 10:e2206768. PubMed
  47. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  48. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  49. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  50. Hsieh MS, et al. 2023. NPJ Vaccines. 8:82. PubMed
  51. Zhang AQ, et al. 2023. Nat Biomed Eng. . PubMed
  52. Shi Y, et al. 2020. Med Sci Monit. 26:e923328. PubMed
  53. Smith NR, et al. 2017. Cell Mol Gastroenterol Hepatol. 0.395138889. PubMed
  54. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  55. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  56. Chang T, et al. 2017. PLoS Pathog. 10.1371/journal.ppat.1006485. PubMed
  57. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  58. García-Prat L, et al. 2020. Nat Cell Biol. 22:1307. PubMed
  59. Tatsuguchi T, et al. 2022. Int Immunol. 34:277. PubMed
  60. Pan J, et al. 2021. Mol Ther Nucleic Acids. 26:970. PubMed
  61. Helms EJ, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  62. Huck NA, et al. 2021. J Neurosci. 41:4349. PubMed
  63. Wu Q, et al. 2021. Cancer Commun (Lond). Online ahead of prin. PubMed
  64. Ma Q, et al. 2021. Clin Transl Immunology. 10:e1300. PubMed
  65. Yagishita Y, et al. 2020. Cell Mol Gastroenterol Hepatol. . PubMed
  66. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  67. Wagner G, et al. 2017. Sci Rep. 7:40881. PubMed
  68. Weeden C, et al. 2017. PLoS Biol. 10.1371/journal.pbio.2000731. PubMed
  69. Hilliard K, et al. 2015. Infect Immun . 83: 4015 - 4027. PubMed
  70. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  71. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  72. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  73. Mansouri N, et al. 2019. JCI Insight. 4:e128060. PubMed
  74. Kim YS, et al. 2021. Cell Death Dis. 12:307. PubMed
  75. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  76. Manivasagam S, et al. 2022. J Immunol. 208:1341. PubMed
  77. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  78. Vila Ellis L, et al. 2020. Dev Cell. 617:52. PubMed
  79. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  80. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  81. White MPJ, et al. 2020. Front Immunol. 11:1830. PubMed
  82. Saito S, et al. 2020. Nutrients. 12:. PubMed
  83. Fu Y, et al. 2020. Mol Ther. 1214:28. PubMed
  84. Wang B, et al. 2017. EBioMedicine. 10.1016/j.ebiom.2017.03.041. PubMed
  85. Kaczmarek–Hájek K, et al. 2018. Elife. 7:e36217. PubMed
  86. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  87. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  88. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  89. Kobayashi H, et al. 2020. STAR Protoc. 1:100078. PubMed
  90. Little DR, et al. 2021. Nat Commun. 12:2509. PubMed
  91. Bhopale VM, et al. 2021. J Appl Physiol (1985). 130:1604. PubMed
  92. Zheng L, et al. 2022. J Neuroinflammation. 19:128. PubMed
  93. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  94. Britschgi A, et al. 2017. Nature. 541:541-545. PubMed
  95. Valds-Mora F, et al. 2021. Cell Reports. 35(2):108945. PubMed
  96. DellOrso S, et al. 2021. STAR Protocols. 2(2):100451. PubMed
  97. Pan J, et al. 2020. J Neuroinflammation. 17:97. PubMed
  98. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  99. Garber C, et al. 2018. Nat Immunol. 19:151. PubMed
  100. Campanario S, et al. 2021. Front Cell Dev Biol. 8:620409. PubMed
  101. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  102. Jiang YH, et al. 2020. J Mol Cell Cardiol. 138:115. PubMed
  103. Wang B,et al. 2017. Cell Discov.. 10.1038/celldisc.2017.36. PubMed
  104. Solanas G, et al. 2017. Cell. 170:678. PubMed
  105. Dubey LK, et al. 2019. Cell Rep. 27:2442. PubMed
  106. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  107. Galvão I, et al. 2018. Front Immunol. 9:142. PubMed
  108. Mizuochi C, et al. 2012. PLoS One. 7:e35763. PubMed
  109. Gigliotti J, et al. 2013. J Am Soc Nephrol. 24:1451. PubMed
  110. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  111. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  112. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  113. McGowan SE, et al. 2018. Am J Physiol Lung Cell Mol Physiol. 315:L102. PubMed
  114. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  115. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  116. Yang R, et al. 2022. Front Pharmacol. 13:774440. PubMed
  117. Fix DK, et al. 2021. Aging Cell. 20:e13448. PubMed
  118. Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
  119. Zhu L, et al. 2021. Stem Cell Res Ther. 12:408. PubMed
  120. Onder L et al. 2017. Immunity. 47(1):80-92 . PubMed
  121. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  122. Kimbrough D, et al. 2018. J Mol Cell Cardiol. 119:51. PubMed
  123. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  124. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  125. Wang W, et al. 2020. Immunity. 51(6):1102-1118.e7.. PubMed
  126. Huang CH, et al. 2020. Adv Ther (Weinh). 3:. PubMed
  127. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  128. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  129. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  130. Basu A, et al. 2021. Cancer Immunol Res. Online ahead of print. PubMed
  131. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  132. Allen S, et al. 2011. J Virol. 85:11448. PubMed
  133. Jaworska K, et al. 2015. J Immunol. 194:325. PubMed
  134. Furuya Y, et al. 2015. PLoS Pathog. 11: 1005180. PubMed
  135. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  136. Cain MP, et al. 2020. Dis Model Mech. 13:00. PubMed
  137. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  138. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  139. Yen Y, et al. 2008. J Virol. 82:12312. PubMed
  140. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  141. Son NH, et al. 2018. J Clin Invest. 128:4329. PubMed
  142. Ellegast JM, et al. 2022. Cancer Discov. 12:1760. PubMed
  143. Liu T, et al. 2022. Front Immunol. 13:901349. PubMed
  144. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  145. Manco R, et al. 2021. Nat Commun. 12:3074. PubMed
  146. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  147. Berg AL, et al. 2022. Cancers (Basel). 14:. PubMed
  148. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  149. McCoy S 2015. Am J Physiol Lung Cell Mol Physiol. 309: L463-L474. PubMed
  150. Kellish P, et al. 2019. J Clin Invest. 130:2279. PubMed
  151. Magri G et al. 2017. Immunity. 47(1):118-134 . PubMed
  152. Sela Y, et al. 2021. Elife. 10: . PubMed
  153. Ishii H, et al. 2012. Cell Death Dis. 9;3:e363. PubMed
  154. Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
  155. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  156. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  157. Pascual G, et al. 2021. Nature. 599:485. PubMed
  158. Kolodziejczyk AA, et al. 2020. Nat Med. 26:1899. PubMed
  159. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  160. Chu X, et al. 2021. Front Cell Dev Biol. 9:671841. PubMed
  161. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  162. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  163. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  164. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  165. Kobayashi H, et al. 2020. Cell Reports. 28(1):145-158.e9.. PubMed
  166. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  167. Jin L, et al. 2022. J Immunol Res. 2022:7222638. PubMed
  168. Koyama T, et al. 2022. Curr Issues Mol Biol. 44:3146. PubMed
  169. Evgin L, et al. 2022. Sci Transl Med. 14:eabn2231. PubMed
  170. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  171. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  172. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  173. van Gastel N, et al. 2020. Cell Metabolism. 32(3):391-403.e6. PubMed
  174. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  175. Shen DD, et al. 2022. Mol Cancer. 21:75. PubMed
  176. Zhu J, et al. 2021. Cancer Cell Int. 21:529. PubMed
  177. Yuan M, et al. 2022. Oxid Med Cell Longev. 2022:5479491. PubMed
  178. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  179. Li J, et al. 2020. Development. :. PubMed
  180. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  181. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  182. Li S, et al. 2019. Front Neurol. 1.036805556. PubMed
  183. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  184. Mohammadpour H, et al. 2021. Cell Rep. 37:109883. PubMed
  185. Zhu S, et al. 2022. EBioMedicine. 80:104060. PubMed
  186. Sung PS, et al. 2022. JCI Insight. :. PubMed
  187. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  188. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  189. Wang W, et al. 2021. STAR Protocols. 2(3):100756. PubMed
  190. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  191. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  192. Smith NR, et al. 2018. Cell Mol Gastroenterol Hepatol. 6:79. PubMed
  193. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  194. Nian Z, et al. 2021. Clin Cancer Res. 27:6026. PubMed
  195. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  196. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  197. Ognjenovic NB, et al. 2020. Dev Cell. 55:544. PubMed
  198. Gu H, et al. 2021. Elife. 10:. PubMed
  199. Hendee K, et al. 2021. Aging (Albany NY). 13:7781. PubMed
  200. Issah Y, et al. 2021. Elife. 10:. PubMed
  201. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  202. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  203. Rai S, et al. 2022. Nat Commun. 13:5346. PubMed
  204. Fan X, et al. 2020. Acta Physiol (Oxf). 230:e13475. PubMed
  205. Fang Y, et al. 2022. Development. 149:. PubMed
  206. Boyce M, et al. 2022. Cells. 11:. PubMed
  207. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  208. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  209. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  210. Béchade C, et al. 2020. Glia. . PubMed
  211. Nguyen HX et al. 2017. J Neurosci. 37(38):9269-9287 . PubMed
  212. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  213. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  214. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  215. Li Q, et al. 2022. J Biol Chem. :101753. PubMed
  216. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  217. Andreou T, et al. 2021. J Immunother Cancer. 9:. PubMed
  218. Rochford I, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 321:L686. PubMed
  219. Sheng J, et al. 2021. eLife. 10:00. PubMed
  220. Moreno M et al. 2014. The Journal of Neuroscience. 34(24):8175-85 . PubMed
  221. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  222. Dourcy M, et al. 2020. Mucosal Immunol. 13:799. PubMed
  223. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  224. Hussein M, et al. 2015. PLoS One. 10: 0135218. PubMed
  225. Gigliotti J, et al. 2015. J Am Soc Nephrol. 26: 2470 - 2481. PubMed
  226. Serr I, et al. 2016. Nat Commun. 7:10991. PubMed
  227. Gerner-Mauro KN, et al. 2020. Proc Natl Acad Sci U S A. 117:12182. PubMed
  228. Kimmel JC, et al. 2021. Cell Reports. 35(4):109046. PubMed
  229. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  230. Wu H, et al. 2020. Cell. 180(1):107-121.e17.. PubMed
  231. Muri J, et al. 2020. Cell Reports. 30(13):4399-4417. PubMed
  232. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  233. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  234. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  235. Song X, et al. 2021. FEBS Open Bio. 11:2453. PubMed
  236. Ren X, et al. 2021. Cell Death Dis. 12:484. PubMed
RRID
AB_312978 (BioLegend Cat. No. 103113)
AB_312978 (BioLegend Cat. No. 103114)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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