Analyte Specific Reagent. Analytical and performance characteristics are not established.
- Clone
- A019D5
- Other Names
- IL-7 receptor α chain, IL-7Rα
- Isotype
- Mouse IgG1, κ
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
986004 | 500 µL | 301€ |
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
Product DetailsProduct Details
- Reactivity
- Human
- Formulation
- Phosphate-buffered solution, pH7.2, containing True-Stain Monocyte Blocker™, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
- Concentration
- 100 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
Suggested for Flow Cytometry
- Disclaimer
-
WARNINGS AND PRECAUTIONS
- Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
- All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
- Do not use this reagent beyond the expiration date stated on the label.
- Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
- Avoid prolonged exposure of the reagent or stained cells to light.
Antigen Details
- Antigen References
-
- Sudo T, et al. 1993. Proc Natl Acad Sci U S A. 90:9125-9.
- He YW and Malek TR. 1998. Crit Rev Immunol. 18:503-24.
- Huster KM, et al. 2004. Proc Natl Acad Sci U S A. 101:5610-5.
- Pillai M, et al. 2004. Leuk Lymphoma. 45:2403-8.
- Morrissey PJ, et al. 1989. J Exp Med. 169:707-16.
- Liu W, et al. 2006. J Exp Med. 203:1701-11.
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with purifie... -
PE anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 APC... -
Pacific Blue™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 PE ... -
Brilliant Violet 421™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
FITC anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 APC... -
Alexa Fluor® 488 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 APC... -
APC anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Alexa Fluor® 647 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
PE/Cyanine7 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
PerCP/Cyanine5.5 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Brilliant Violet 570™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
PE/Cyanine5 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Brilliant Violet 650™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Brilliant Violet 711™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD127 (... -
Brilliant Violet 785™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD127 (... -
Brilliant Violet 510™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD127 (... -
Brilliant Violet 605™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
PE/Dazzle™ 594 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Purified anti-human CD127 (IL-7Rα) (Maxpar® Ready)
Human PBMCs stained with 154Sm-anti-CD3 (UCHT1) and 143Nd-an... -
Alexa Fluor® 700 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 PE ... -
Biotin anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 APC... -
APC/Cyanine7 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
APC/Fire™ 750 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 FIT... -
TotalSeq™-A0390 anti-human CD127 (IL-7Rα)
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TotalSeq™-B0390 anti-human CD127 (IL-7Rα)
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TotalSeq™-C0390 anti-human CD127 (IL-7Rα)
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KIRAVIA Blue 520™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with CD3 APC... -
Spark NIR™ 685 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes stained with CD3 FITC and... -
PE/Fire™ 640 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 700 anti-human CD127 (IL-7Rα) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
Spark YG™ 581 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
Brilliant Violet 750™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-D0390 anti-human CD127 (IL-7Rα)
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APC/Fire™ 810 anti-human CD127 (IL-7Rα) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Fire™ 750 anti-human CD127
Typical results from human peripheral blood lymphocytes stai... -
PE anti-human CD127
Typical results from human peripheral blood lymphocytes stai... -
PerCP/Cyanine5.5 anti-human CD127
Typical results from human peripheral blood lymphocytes stai... -
PE/Cyanine7 anti-human CD127
Typical results from human peripheral blood lymphocytes stai... -
Spark Red™ 718 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
GMP PE/Cyanine7 anti-human CD127 (IL-7Rα)
Typical results from human peripheral blood lymphocytes stai... -
PE/Fire™ 744 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 780 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 806 anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu... -
Spark PLUS B550™ anti-human CD127 (IL-7Rα)
Human peripheral blood lymphocytes were stained with anti-hu...
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