Brilliant Violet 650™ anti-human CD38 Antibody, CD38, HIT2

Pricing & Availability

Clone: HIT2 (See other available formats)
Regulatory Status: RUO
Workshop: III 155
Other Names: T10, ADP-ribosyl cyclase
Isotype: Mouse IgG1, κ
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Product Citations: publications

HIT2_BV-650_CD38_FC_041624 — Human peripheral blood lymphocytes were stained with anti-human CD38 (clone HIT2) Brilliant Violet 650™ (filled histogram) or mouse IgG1, κ Brilliant Violet 650™ isotype control (open histogram).

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303561

25 tests

168€

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303562

100 tests

280€

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Description

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Human
Reported Reactivity: Chimpanzee, Horse, Cow
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 650™ under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Brilliant Violet 650™ excites at 405 nm and emits at 645 nm. The bandpass filter 660/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 650™ is a trademark of Sirigen Group Ltd.

Learn more about Brilliant Violet™.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser: Violet Laser (405 nm)
Application Notes: Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections⁶ and spatial biology (IBEX)^10,11.
RRID: AB_3662213 (BioLegend Cat. No. 303561)
AB_3662213 (BioLegend Cat. No. 303562)

Antigen Details

Structure: ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
Distribution: T cells, B cells, NK, myeloid, plasma, and dendritic cells
Function: Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
Ligand/Receptor: CD31, hyaluronic acid
Cell Type: B cells, Dendritic cells, NK cells, Plasma cells, T cells
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.
Gene ID: 952 View all products for this Gene ID
UniProt: View information about CD38 on UniProt.org

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PE/Dazzle™ 594 anti-human CD38	HIT2	FC
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TotalSeq™-A0389 anti-human CD38	HIT2	PG
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APC/Fire™ 750 anti-human CD38	HIT2	FC
TotalSeq™-B0389 anti-human CD38	HIT2	PG
APC/Fire™ 810 anti-human CD38	HIT2	FC
Spark NIR™ 685 anti-human CD38 Antibody	HIT2	FC
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PerCP/Cyanine5.5 anti-human CD38	HIT2	FC
APC anti-human CD38	HIT2	FC
APC/Fire™ 750 anti-human CD38	HIT2	FC
PE/Cyanine7 anti-human CD38	HIT2	FC
GMP PE anti-human CD38	HIT2	FC
GMP FITC anti-human CD38	HIT2	FC
Pacific Blue™ anti-human CD38	HIT2	FC
Pacific Blue™ anti-human CD38	HIT2	FC
GMP APC/Fire™ 750 anti-human CD38	HIT2	FC
GMP PE/Dazzle™ 594 anti-human CD38	HIT2	FC
GMP APC anti-human CD38	HIT2	FC
GMP PE/Cyanine7 anti-human CD38	HIT2	FC
Spark Blue™ 515 anti-human CD38	HIT2	FC
GMP Pacific Blue™ anti-human CD38	HIT2	FC
Spark Violet™ 423 anti-human CD38	HIT2	FC
Brilliant Violet 650™ anti-human CD38	HIT2	FC
Spark PLUS B550™ anti-human CD38	HIT2	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 04/16/2024

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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