Analyte Specific Reagent. Analytical and performance characteristics are not established.
- Clone
- VI-PL2
- Other Names
- Integrin β3, gpIIIa
- Isotype
- Mouse IgG1, κ
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
988002 | 500 µL | 200€ |
CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
Product DetailsProduct Details
- Reactivity
- Human
- Formulation
- Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 100 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
Suggested for Flow Cytometry
- Disclaimer
-
WARNINGS AND PRECAUTIONS
- Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
- All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
- Do not use this reagent beyond the expiration date stated on the label.
- Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
- Avoid prolonged exposure of the reagent or stained cells to light.
Antigen Details
- Antigen References
-
- Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers.
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD61
MDA-MB-231 breast cancer cells were stained with anti-CD61 (... Human peripheral blood platelets stained with purified VI-PL... -
FITC anti-human CD61
Human peripheral blood platelets stained with VI-PL2 FITC -
PE anti-human CD61
Human peripheral blood platelets stained with VI-PL2 PE -
Alexa Fluor® 647 anti-human CD61
Human peripheral blood platelets stained with VI-PL2 Alexa F... MDA-MB435 breast cancer cell line was stained with 20 µg/mL ... -
PerCP anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
APC anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
Purified anti-human CD61 (Maxpar® Ready)
Human PBMCs stained with 150Nd-anti-CD61 (VI-PL2). B lymphoc... -
PE/Cyanine7 anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
PerCP/Cyanine5.5 anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
APC/Fire™ 750 anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
Alexa Fluor® 700 anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
TotalSeq™-A0372 anti-human CD61
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PE/Dazzle™ 594 anti-human CD61
Human peripheral blood platelets were stained with CD61 (clo... -
TotalSeq™-C0372 anti-human CD61
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TotalSeq™-D0372 anti-human CD61
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FITC anti-human CD61
Typical results from human peripheral blood platelets staine... -
TotalSeq™-B0372 anti-human CD61
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PE anti-human CD61
Typical results from human peripheral blood platelets staine... -
Brilliant Violet 510™ anti-human CD61
Human peripheral blood platelets were stained with anti-hum... -
Brilliant Violet 650™ anti-human CD61
Human peripheral blood platelets were stained with anti-huma...
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