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PE anti-human CD105 (Endoglin) Recombinant Antibody

Pricing & Availability
Clone
QA19A14 (See other available formats)
Regulatory Status
RUO
Other Names
Endoglin, Cell surface MJ7/18 antigen, END, Edg, ENG, HHT1, ORW1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA19A14_PE_CD105_Antibody_111621
Human monocytic cell line THP-1 was stained with anti-human CD105 (clone QA19A14) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
  • QA19A14_PE_CD105_Antibody_111621
    Human monocytic cell line THP-1 was stained with anti-human CD105 (clone QA19A14) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
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366003 25 tests 98€
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366004 100 tests 194€
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Description

Endoglin (CD105) is a type I membrane glycoprotein that is part of the TGF beta receptor complex. It is expressed in vascular endothelial tissue as well as a variety of other tissues. Endoglin may also be involved in the cytoskeletal organization affecting cell morphology and migration.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Immunogen
EDG (CD105) isolated from acute lymphoblastic leukemia cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2904399 (BioLegend Cat. No. 366003)
AB_2904399 (BioLegend Cat. No. 366004)

Antigen Details

Cell Type
Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area
Angiogenesis, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Li C, et al. 2003. Br J Cancer. 88:1424.
  2. Sanz-Rodriguez F, et al. 2004. J Biol Chem. 279(31):32858-68.
  3. Takahashi N, et al. 2001. Clin Cancer Res. 7(3):524-32.
  4. Seon BK, et al. 1997. Clin Cancer Res. 3(7):1031-44.
  5. Haruta Y & Seon BK. 1986. Proc Natl Acad Sci U S A. 83: 7898-902.
Gene ID
2022 View all products for this Gene ID
UniProt
View information about CD105 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/15/2021

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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