- Clone
- 5F10B29 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CKR1, CD191, HM145, SCYAR1, CMKRB1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
362903 | 25 tests | 113€ | ||||
362904 | 100 tests | 268€ |
CD191, also known as CCR1, is a 41 kD, G-protein coupled receptor expressed predominantly by monocytes. CCR1 is also expressed by a subset of T cells and eosinophils. CCR1 positive cells can migrate in response to a CCL3 and CCL5 gradient. CCR1 knock-out studies suggest that this molecule plays an important role in inflammation and susceptibility to viruses and parasites.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CCR1 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_2563897 (BioLegend Cat. No. 362903)
AB_2563897 (BioLegend Cat. No. 362904)
Antigen Details
- Structure
- G-protein coupled receptor, seven transmembrane protein, 41 kD
- Distribution
-
Monocytes, macrophages, subset of T cells, eosinophils
- Function
- Regulates migration of cells in response to CCL3 and CCL5
- Ligand/Receptor
- CCL3 and CCL5
- Cell Type
- Eosinophils, Macrophages, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Su SB, et al. 1996. J. Leuko. Biol. 60:658.
2. Su S, et al. 1997. Blood. 90:605.
3. Ayehunie S, et al. 1997. Blood. 90:1379.
4. Gerard C, et al. 1997. J. Clin. Invest. 100:2022.
5. Tiffany HL, et al. 1998. J. Immunol. 160:1385.
6. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194.
7. Bednar F, et al. 2014. J. Immunol. 192:5305. - Gene ID
- 1230 View all products for this Gene ID
- UniProt
- View information about CD191 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD191 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD191 (CCR1) | 5F10B29 | FC |
PE anti-human CD191 (CCR1) | 5F10B29 | FC |
Alexa Fluor® 488 anti-human CD191 (CCR1) | 5F10B29 | FC |
APC anti-human CD191 (CCR1) | 5F10B29 | FC |
PerCP/Cyanine5.5 anti-human CD191 (CCR1) | 5F10B29 | FC |
FITC anti-human CD191 (CCR1) | 5F10B29 | FC |
APC/Fire™ 750 anti-human CD191 (CCR1) | 5F10B29 | FC |
PE/Cyanine7 anti-human CD191 (CCR1) | 5F10B29 | FC |
APC/Cyanine7 anti-human CD191 (CCR1) | 5F10B29 | FC |
TotalSeq™-D1261 anti-human CD191 (CCR1) | 5F10B29 | PG |
TotalSeq™-A1261 anti-human CD191 (CCR1) | 5F10B29 | PG |
TotalSeq™-B1261 anti-human CD191 (CCR1) | 5F10B29 | PG |
TotalSeq™-C1261 anti-human CD191 (CCR1) | 5F10B29 | PG |
PE/Dazzle™ 594 anti-human CD191 (CCR1) | 5F10B29 | FC |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with purified ... -
PE anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 (CC... -
Alexa Fluor® 488 anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 (cl... -
APC anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 (cl... -
PerCP/Cyanine5.5 anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 Per... -
FITC anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 FIT... -
APC/Fire™ 750 anti-human CD191 (CCR1)
Human peripheral blood monocytes were treated with human Tru... -
PE/Cyanine7 anti-human CD191 (CCR1)
Human TruStain FcX™ (Cat. No. 422302) treated human peripher... -
APC/Cyanine7 anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with CD191 (cl... -
TotalSeq™-D1261 anti-human CD191 (CCR1)
-
TotalSeq™-A1261 anti-human CD191 (CCR1)
-
TotalSeq™-B1261 anti-human CD191 (CCR1)
-
TotalSeq™-C1261 anti-human CD191 (CCR1)
-
PE/Dazzle™ 594 anti-human CD191 (CCR1)
Human peripheral blood monocytes were stained with anti-huma...
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