- Clone
- BY88 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V BP173
- Other Names
- Ber-H2, Ki-1, TNFRSF8
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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333906 | 100 tests | 205€ |
CD30, also known as Ki-1 antigen, lymphoid activation antigen CD30, and tumor necrosis factor receptor superfamily member 8 is a type I transmembrane receptor that contains four TNF receptor domains with an approximate molecular weight of 64 kD. CD30 is highly expressed on Hodgkins and Reed-Sternberg cells as well as activated, but not resting, T and B cells. CD30 has been shown to interact with a number of proteins including TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, and CD30 ligand (CD153). Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD30 boosted with THP-1 cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Additional reported application: in combination with IL-2 and PMA to induce T cell clone proliferation.
- Application References
-
- Leca G, et al. 1994. Cell. Immunol. 156:230.
- Product Citations
-
- RRID
-
AB_2207595 (BioLegend Cat. No. 333906)
Antigen Details
- Structure
- Type I transmembrane receptor and member of the TNF receptor superfamily that contains 4 TNF receptor domains; predicted molecular weight approximately 64 kD
- Distribution
-
Highly expressed on Hodgkins and Reed-Sternberg cells and activated, but not resting, T cells and B cells.
- Function
- Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.
- Interaction
- TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, CD30 ligand (CD153)
- Ligand/Receptor
- CD30 Ligand (CD153)
- Cell Type
- B cells, Embryonic Stem Cells, Tregs
- Biology Area
- Immunology, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Durkop H, et al. 1992. Cell 68:421.
2. Aizawa S, et al. 1997. J. Biol. Chem. 272:2042.
3. Stein H, et al. 1982. Int. J. Cancer 30:445. - Gene ID
- 943 View all products for this Gene ID
- UniProt
- View information about CD30 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD30 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD30 | BY88 | FC |
FITC anti-human CD30 | BY88 | FC |
PE anti-human CD30 | BY88 | FC |
APC anti-human CD30 | BY88 | FC |
PerCP/Cyanine5.5 anti-human CD30 | BY88 | ICFC |
TotalSeq™-A0028 anti-human CD30 | BY88 | PG |
APC/Fire™ 750 anti-human CD30 | BY88 | FC |
PE/Cyanine7 anti-human CD30 | BY88 | FC |
TotalSeq™-C0028 anti-human CD30 | BY88 | PG |
TotalSeq™-B0028 anti-human CD30 | BY88 | PG |
TotalSeq™-D0028 anti-human CD30 | BY88 | PG |
APC anti-human CD30 | BY88 | FC |
FITC anti-human CD30 | BY88 | FC |
PE anti-human CD30 | BY88 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD30
Human T lymphoma cell line Hut-78 stained with purified BY88... -
FITC anti-human CD30
Human T lymphoma cell line Hut-78 stained with BY88 FITC -
PE anti-human CD30
Human T lymphoma cell line Hut-78 stained with PE BY88 -
APC anti-human CD30
Human T lymphoma cell line Hut-78 stained with APC BY88 -
PerCP/Cyanine5.5 anti-human CD30
HuT-78 cells (Human T lymphoma cell line) were stained with ... -
TotalSeq™-A0028 anti-human CD30
-
APC/Fire™ 750 anti-human CD30
HuT-78 cells (Human T lymphoma cell line) were stained with ... -
PE/Cyanine7 anti-human CD30
HuT-78 cells (Human T lymphoma cell line) were stained with ... -
TotalSeq™-C0028 anti-human CD30
-
TotalSeq™-B0028 anti-human CD30
-
TotalSeq™-D0028 anti-human CD30
-
APC anti-human CD30
Typical results from HDLM-2 cells (a human lymphoma cell lin... -
FITC anti-human CD30
Typical results from HDLM-2 cells (a human lymphoma cell lin... -
PE anti-human CD30
Typical results from HDLM-2 cells (a human lymphoma cell lin...
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