Loading...

PE/Cyanine7 anti-mouse F4/80 Antibody

Pricing & Availability
Clone
BM8 (See other available formats)
Regulatory Status
RUO
Other Names
EMR1, Ly71
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
BM8_PECy7_122607
Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
  • BM8_PECy7_122607
    Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
123113 25 µg 84€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
123114 100 µg 243€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

F4/80, also known as EMR1 or Ly71, is a 160 kD glycoprotein of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 has been widely used as a murine macrophage marker. It is expressed on a majority of tissue macrophages, including macrophages in the lung, gut, peritoneal cavity, thymus, and red pulp of the spleen, Kupffer cells, Langerhans cells, microglia, and certain dendritic cells. It is not expressed on macrophages located in the T cell areas of the spleen, lymph node, or Peyer's patch. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for the induction of CD8+ T cells-mediated peripheral tolerance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine macrophages
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1,2 and formalin-fixed paraffin-embedded sections6,7, Western blotting, and spatial biology (IBEX)12,13.

Application References
  1. Schaller E, et al. 2002. Mol. Cell. Biol. 22:8035. (IHC)
  2. Stevceva L, et al. 2001. BMC Clin Pathol. 1:3. (IHC)
  3. Kobayashi M, et al.2008. J. Leukoc. Biol. 83:1354. PubMed
  4. Poeckel D, et al. 2009. J. Biol Chem. 284:21077. PubMed
  5. Glass AM, et al. 2013. J. Immunol. 190:4830. PubMed
  6. Koehm S, et al. 2007. J. Allergy Clin. Immunol. 120:570. (IHC)
  7. Rankin AL, et al. 2010. J. Immunol. 184:1526. (IHC)
  8. Sasi SP, et al. 2014. J Biol Chem. 289:14178. PubMed
  9. Thakus VS, et al. 2014. Toxicol Lett. 230:322. PubMed
  10. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
  11. Hirakawa H, et al. 2015. PLoS One. 10:119360. PubMed
  12. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  13. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  2. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  3. Sierro F, et al. 2017. Immunity. 47:374. PubMed
  4. Fan G, et al. 2021. Cell Death Dis. 12:73. PubMed
  5. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  6. Su Y, et al. 2022. J Hematol Oncol. 15:99. PubMed
  7. Taranto D, et al. 2021. Curr Protoc. 1:e147. PubMed
  8. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  9. Gerlach BD, et al. 2021. Cell Metab. 33:2445. PubMed
  10. Mills EL, et al. 2022. Cell Metab. 34:140. PubMed
  11. Gadipudi LL, et al. 2022. Clin Sci (Lond). 136:643. PubMed
  12. Van Deren DA, et al. 2022. Development. 149: . PubMed
  13. Liu K, et al. 2022. J Cell Biol. 221: . PubMed
  14. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  15. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  16. Silva Pereira S, et al. 2022. Elife. 11: . PubMed
  17. Akalu YT, et al. 2022. Elife. 11: . PubMed
  18. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  19. Morrow RJ, et al. 2022. Cells. 11: . PubMed
  20. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  21. Niu J, et al. 2023. Nat Commun. 14:642. PubMed
  22. Chun J, et al. 2023. Cancers (Basel). 15: . PubMed
  23. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  24. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  25. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  26. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  27. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  28. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  29. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  30. Krasniewski LK, et al. 2022. Elife. 11:. PubMed
  31. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  32. Wu Z, et al. 2023. EMBO Rep. 24:e56524. PubMed
  33. Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed
  34. Aso K, et al. 2023. Nat Commun. 14:984. PubMed
  35. Zhong WJ, et al. 2023. J Transl Med. 21:179. PubMed
  36. Cheng K, et al. 2023. Small. 19:e2300125. PubMed
  37. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  38. Seclì L, et al. 2023. J Immunother Cancer. 11:. PubMed
  39. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  40. Ishida K, et al. 2023. Front Immunol. 14:1111729. PubMed
  41. Brigo N, et al. 2023. Cells. 12:. PubMed
  42. Tsugawa H, et al. 2023. PLoS Pathog. 19:e1011139. PubMed
  43. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  44. Lauterbach MA, et al. 2020. Immunity. 51(6):997-1011.e7.. PubMed
  45. Poh AR, et al. 2017. Cancer Cell. 31:563. PubMed
  46. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  47. Yonemitsu K, et al. 2022. Sci Rep. 12:12007. PubMed
  48. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  49. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  50. Dando SJ, et al. 2021. Invest Ophthalmol Vis Sci. 62:10. PubMed
  51. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  52. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  53. Aggen DH, et al. 2020. Clin Cancer Res. . PubMed
  54. Cornax I, et al. 2021. Microorganisms. 9:00. PubMed
  55. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  56. Sadek J, et al. 2021. EMBO Mol Med. 13:e13591. PubMed
  57. Frank AC, et al. 2021. Theranostics. 11:7570. PubMed
  58. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  59. Kesavan R, et al. 2021. Int J Mol Sci. 22:. PubMed
  60. Sasse C, et al. 2022. Pathogens. 11:. PubMed
  61. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  62. Weigert A, et al. 2022. Nat Commun. 13:6078. PubMed
  63. Saxena A, et al. 2013. J Immunol. 191:4838. PubMed
  64. Giordano C, et al. 2014. Hum Mol Genet. . PubMed
  65. Shang W, et al. 2019. J Diabetes Res. 2019:5641271. PubMed
  66. Shikatani EA et al. 2019. Cell Rep. 27(8):2304-2312 . PubMed
  67. Andreas N, et al. 2021. Arthritis Res Ther. 23:222. PubMed
  68. Huard A, et al. 2021. J Immunol. 206:1058. PubMed
  69. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  70. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  71. Cheng G, et al. 2021. iScience. 24:102673. PubMed
  72. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  73. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  74. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  75. Currier MA, et al. 2017. Oncotarget. 8:17412. PubMed
  76. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  77. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  78. Starkl P, et al. 2020. Immunity. 53(4):793-804.e9. PubMed
  79. Damal Villivalam S, et al. 2020. Nat Commun. 4313:11. PubMed
  80. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  81. Luo W, et al. 2019. Mol Med Rep. 20:1007. PubMed
  82. Shimoda A, et al. 2017. Biochem Biophys Res Commun. 10.1016/j.bbrc.2017.07.126. PubMed
  83. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  84. Sive J, et al. 2015. Leukemia. . PubMed
  85. Sharma S, et al. 2015. J Immunol. 194:5529. PubMed
  86. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  87. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  88. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  89. Qu J, et al. 2018. J Immunol Res. 2018:7519856. PubMed
  90. Terashima Y, et al. 2020. Nat Commun. 11:609. PubMed
  91. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  92. Wu X, et al. 2021. Elife. 10:. PubMed
  93. Roy R, et al. 2022. Elife. 11:. PubMed
  94. Stutchfield B, et al. 2015. Gastroenterology. 149: 1896-1909.e14. PubMed
  95. Jondle C, et al. 2016. J Immunol. 196: 3088-3096. PubMed
  96. Szafran BN, et al. 2021. Chemical Research in Toxicology. 34(6):1556-1571. PubMed
  97. Linde N, et al. 2018. Nat Commun. 9:21. PubMed
  98. Xiao Y, et al. 2022. Clin Transl Med. 12:e1071. PubMed
  99. Smith AS, et al. 2022. J Immunother Cancer. 10:. PubMed
  100. Tomlinson KL, et al. 2021. Nat Commun. 12:1399. PubMed
  101. Wu MY, et al. 2021. Autophagy. 17:1096. PubMed
  102. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  103. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  104. Tay S, et al. 2014. J Immunol. 193:2087. PubMed
  105. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  106. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  107. Zheng Z, et al. 2020. Cell Death Dis. 0.684722222. PubMed
  108. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  109. Lu X, et al. 2020. Sci Transl Med. 12:. PubMed
  110. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  111. Ganguly K, et al. 2022. Front Immunol. 13:930449. PubMed
  112. Weber G, et al. 2014. J Exp Med. 211:1243. PubMed
  113. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  114. Torroella-Kouri M, et al. 2009. Cancer Res. 69:4800. PubMed
  115. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  116. Xu X, et al. 2018. Cell. 175:1336. PubMed
  117. Oertel S, et al. 2017. Cell Mol Life Sci. 10.1007/s00018-017-2518-9. PubMed
  118. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  119. Yong L, et al. 2022. Nat Commun. 13:4255. PubMed
  120. Golden TN, et al. 2022. Front Pharmacol. 12:761496. PubMed
  121. Garland KM, et al. 2021. Front Immunol. 12:753472. PubMed
  122. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  123. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  124. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  125. Volberding PJ, et al. 2021. Cell Reports. 35(8):109160. PubMed
  126. Mojumdar K, et al. 2014. EMBO Mol Med. 6:1476. PubMed
  127. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  128. Medler TR et al. 2018. Cancer cell. 34(4):561-578 . PubMed
  129. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  130. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  131. Aktories P, et al. 2022. Cell Rep Methods. 2:100260. PubMed
  132. Chiu Y, et al. 2014. J Immunol. 193:2207. PubMed
  133. Hamilton J, et al. 2015. J Immunol. 194:5022. PubMed
  134. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  135. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  136. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  137. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  138. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  139. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  140. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  141. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  142. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  143. Sun P, et al. 2022. Nat Commun. 13:6562. PubMed
  144. Pathania AS, et al. 2022. Mol Ther Oncolytics. 25:308. PubMed
  145. Bachy S, et al. 2022. iScience. 25:103758. PubMed
  146. Anderson AE, et al. 2022. NPJ Regen Med. 7:6. PubMed
  147. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  148. Park HB, et al. 2020. Nat Microbiol. 1319:5. PubMed
  149. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  150. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  151. Ren Y, et al. 2020. Stem Cell Res Ther. 0.743055556. PubMed
  152. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  153. Maisel D, et al. 2016. PLoS One. 11: 0159716. PubMed
  154. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  155. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  156. Efremova M, et al. 2018. Nat Commun. 9:32. PubMed
  157. Su W et al. 2019. Cancer Cell. 36(2):139-155 . PubMed
  158. Quenum Zangbede FO, et al. 2018. J Neurosci. 38:6737. PubMed
  159. Roy AG, et al. 2021. Int J Mol Sci. 22:. PubMed
  160. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  161. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  162. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  163. Nabet BY et al. 2017. Cell. 170(2):352-366 . PubMed
  164. Ponzetta A, et al. 2020. Cell. 178(2):346-360.e24.. PubMed
  165. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  166. Vasamsetti SB, et al. 2018. Immunity. 49:93. PubMed
  167. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  168. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  169. Cheng HW, et al. 2022. Nat Commun. 13:2027. PubMed
  170. Stevenson ER, et al. 2022. J Pharmacol Exp Ther. 382:356. PubMed
  171. Baranwal G, et al. 2021. Physiol Rep. 9:e15094. PubMed
  172. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  173. Fujii T, et al. 2021. Bone Res. 9:4. PubMed
  174. Li J, et al. 2020. FASEB J. 34:3091. PubMed
  175. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  176. Heim CE, et al. 2020. Nature Microbiology. 5(10):1271-1284. PubMed
  177. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  178. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  179. Song M, et al. 2013. Am J Pathol. 182:1308. PubMed
  180. Clemente C, et al. 2018. Nat Commun. 9:910. PubMed
  181. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  182. Li C, et al. 2018. Cell. 174:285. PubMed
  183. Nalbandian A, et al. 2017. Inflammation. 40:21:00. PubMed
  184. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  185. Fletcher P, et al. 2021. J Toxicol Environ Health A. 84:152. PubMed
  186. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  187. INAGAWA H, et al. 2016. In Vivo. 30: 205 - 211. PubMed
  188. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  189. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  190. Grayczyk JP et al. 2017. Cell host & microbe. 22(5):678-687 . PubMed
  191. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  192. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  193. Rao L, et al. 2020. Nat Commun. 11:4909. PubMed
  194. Bell CR, et al. 2022. Nat Commun. 13:2063. PubMed
  195. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  196. Yun H, et al. 2020. Immunity. 53(5):1050-1062.e5. PubMed
  197. Chan M, et al. 2013. J Cell Sci. 126:3948. PubMed
  198. Frank AC, et al. 2019. Nat Commun. 10:1135. PubMed
  199. Zhang C, et al. 2018. Cell Res. 28:323. PubMed
  200. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  201. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  202. Zhang Z, et al. 2020. Nature. 579:415. PubMed
  203. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  204. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  205. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  206. Urbanska AM, et al. 2020. Cancer Biother Radiopharm. 35:459. PubMed
  207. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  208. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  209. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  210. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  211. Bajracharya B, et al. 2022. Biomed Res Int. 2022:9928362. PubMed
  212. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  213. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  214. Zhang L, et al. 2020. Cell. 442:181. PubMed
  215. Sangaletti S, et al. 2021. iScience. 24(6):102510. PubMed
  216. Sheng J, et al. 2021. eLife. 10:00. PubMed
  217. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  218. Kwon H, Kim S 2016. Cell Death Dis. 7:22285. PubMed
  219. Kong P, et al. 2013. Am J Physiol Heart Circ Physiol. 305:1363. PubMed
  220. Li S, et al. 2017. Applied Materials & Interfaces. 10.1021/acsami.7b03160. PubMed
  221. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  222. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  223. Liu Z, et al. 2020. STAR Protoc. 1:100029. PubMed
  224. Ramavath NN, et al. 2021. Front Immunol. 12:786680. PubMed
  225. Shue YT, et al. 2022. Nat Commun. 13:2690. PubMed
  226. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  227. Aguado B, et al. 2015. Sci Rep. 5: 17566. PubMed
  228. Hall JA, et al. 2020. Cell Metabolism. 32(4):665-675.e6. PubMed
  229. Yu YR, et al. 2020. STAR Protocols. 11(3):e0150606. PubMed
  230. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  231. Youssif C, et al. 2018. EMBO Mol Med. 10:e8403. PubMed
  232. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  233. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  234. Pastor Arroyo EM, et al. 2022. Clin Sci (Lond). 136:557. PubMed
  235. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  236. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  237. Nabekura T, et al. 2020. Immunity. 96:52. PubMed
  238. Bae S, et al. 2021. Cell Reports. 35(11):109264. PubMed
  239. Harvey RE et al. 2017. Endocrinology. 158(7):2179-2189 . PubMed
  240. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
  241. Denis C, et al. 2014. Nucleic Acids Res. 42:7370. PubMed
RRID
AB_893478 (BioLegend Cat. No. 123113)
AB_893478 (BioLegend Cat. No. 123114)

Antigen Details

Structure
EGF-TM7 family member, 160 kD glycoprotein
Distribution

Majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen, Kupffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells

Function
Induction of immunological tolerance
Cell Type
Dendritic cells, Langerhans cells, Macrophages, Tregs
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References

1. Austy JM and Gordon S. 1981. Eur. J. Immunol. 11:805.
2. Hume DA, et al. 1983. J. Exp. Med. 158:1522.
3. Ruedl C, et al. 1996. Eur. J. Immunol. 26:1801.
4. McKnight AJ, et al. 1996. J. Biol. Chem. 271:486.
5. Lin HH, et al. 2005. J. Exp. Med. 201:1615.

Gene ID
13733 View all products for this Gene ID
UniProt
View information about F4/80 on UniProt.org

Other Formats

View All F4/80 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 605™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 BM8 FC,IHC,WB
Biotin anti-mouse F4/80 BM8 FC,IHC
FITC anti-mouse F4/80 BM8 FC
PE anti-mouse F4/80 BM8 FC
PE/Cyanine5 anti-mouse F4/80 BM8 FC
PE/Cyanine7 anti-mouse F4/80 BM8 FC
APC anti-mouse F4/80 BM8 FC
APC/Cyanine7 anti-mouse F4/80 BM8 FC
Alexa Fluor® 488 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse F4/80 BM8 FC
PerCP anti-mouse F4/80 BM8 FC
PerCP/Cyanine5.5 anti-mouse F4/80 BM8 FC
Alexa Fluor® 700 anti-mouse F4/80 BM8 FC
Brilliant Violet 421™ anti-mouse F4/80 BM8 FC,IHC-F,SB
Brilliant Violet 510™ anti-mouse F4/80 BM8 FC
Alexa Fluor® 594 anti-mouse F4/80 BM8 IHC-F
Brilliant Violet 785™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 (Maxpar® Ready) BM8 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse F4/80 BM8 FC
Brilliant Violet 650™ anti-mouse F4/80 BM8 FC
Brilliant Violet 711™ anti-mouse F4/80 BM8 FC
APC/Fire™ 750 anti-mouse F4/80 BM8 FC
TotalSeq™-A0114 anti-mouse F4/80 BM8 PG
TotalSeq™-B0114 anti-mouse F4/80 BM8 PG
TotalSeq™-C0114 anti-mouse F4/80 BM8 PG
Spark YG™ 570 anti-mouse F4/80 BM8 IHC-F
KIRAVIA Blue 520™ anti-mouse F4/80 BM8 FC
Ultra-LEAF™ Purified anti-mouse F4/80 BM8 FC,IHC,WB
APC/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark NIR™ 685 anti-mouse F4/80 BM8 FC
Spark Blue™ 550 anti-mouse F4/80 BM8 FC
Brilliant Violet 570™ anti-mouse F4/80 BM8 FC
Brilliant Violet 750™ anti-mouse F4/80 BM8 FC
PE/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark Red™ 718 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Spark Blue™ 574 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Go To Top Version: 2    Revision Date: 10/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account