Purified anti-Annexin A1 Antibody (Previously Covance catalog# MMS-5237)

Pricing & Availability
Clone
74/3 (See other available formats)
Regulatory Status
RUO
Other Names
Lipocortin-1, p35, annexin-1, calpactin-2, calpactin II, lipocortin I, chromobindin-9, annexin I (lipocortin I), phospholipase A2 inhibitory protein
Previously
Covance Catalog# MMS-5237
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
74slas3_Purified_Annexin-1_Antibody_FC_022615
Lipocortin-1 (74/3) and isotype control staining of K562 cells analyzed by flow cytometry. Cells were pretreated with Fix/Perm buffer. A goat anti-mouse-PE conjugate was used as secondary antibody.
  • 74slas3_Purified_Annexin-1_Antibody_FC_022615
    Lipocortin-1 (74/3) and isotype control staining of K562 cells analyzed by flow cytometry. Cells were pretreated with Fix/Perm buffer. A goat anti-mouse-PE conjugate was used as secondary antibody.
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831601 100 µL 220€
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Description

Annexin1 (also known as Lipocortin-1) is a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. Phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins, and leukotrienes. Lipocortin-1 has phospholipase A2 inhibitory activity, thus therefore it is an anti-inflammatory protein.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against AG1523 human fibroblast cells.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Uri A, et al. 2017. Front Immunol. 721:8. PubMed
RRID
AB_2564948 (BioLegend Cat. No. 831601)

Antigen Details

Biology Area
Cell Biology, Neuroinflammation, Neuroscience
Molecular Family
Phospho-Proteins
Gene ID
301 View all products for this Gene ID
UniProt
View information about Annexin A1 on UniProt.org

Related FAQs

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Go To Top Version: 6    Revision Date: 07/09/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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