Purified anti-human CD102 (ICAM-2) Antibody

Pricing & Availability
Clone
W22039A (See other available formats)
Regulatory Status
RUO
Other Names
Intercellular Adhesion Molecule-2, ICAM-2
Isotype
Mouse IgG2a, κ
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Product Citations
publications
W22039A_PURE_CD102_FC_102224
Human peripheral blood leukocytes were stained with purified anti-human CD102 (ICAM-2) (clone W22039A) (left) or purified mouse IgG2a, κ isotype control (right), followed by anti-mouse IgG PE.
  • W22039A_PURE_CD102_FC_102224
    Human peripheral blood leukocytes were stained with purified anti-human CD102 (ICAM-2) (clone W22039A) (left) or purified mouse IgG2a, κ isotype control (right), followed by anti-mouse IgG PE.
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315405 100 µg 82€
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Description

CD102, also known as Intercellular Adhesion Molecule-2, or ICAM-2, is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN, and MAC-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CD102 (ICAM-2) recombinant protein fragment
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Flow cytometry testing showed that clone W22039A does not affect the binding of clones W22038F and CBR-IC2/2 on target cells.

Antigen Details

Structure
55 kD type I transmembrane glycoprotein, Ig superfamily
Distribution

Vascular endothelial cells, lymphocytes, monocytes, platelets

Function
Adhesion, costimulation
Ligand/Receptor
LFA-1, DC-SIGN, MAC-1
Cell Type
Epithelial cells, Lymphocytes, Monocytes, Platelets
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Weber KSC, et al. 2004. Inflammation. 28:177-88.
  2. Barclay A, et al. 1997. The Leukoycte Antigen FactsbookAcademic Press.
  3. Casasnovas JM, et al. 1999. P Natl Acad Sci. USA. 96:3017.
  4. Diamonds MS, et al. 1990. J Cell Biol. 111:3129-39.
Gene ID
3384 View all products for this Gene ID
UniProt
View information about CD102 on UniProt.org
Go To Top Version: 1    Revision Date: 10/22/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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