- Clone
- HIM6 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- VI N-L109
- Other Names
- Neurothelin, Basigin, EMMPRIN
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
306202 | 100 µg | 92€ |
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee, Baboon, Capuchin Monkey
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human PBMCs
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µl volume or 100 µl of whole blood. For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 0.5 - 10.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications (for the relevant formats) include: inhibition of T cell activation2, immunohistochemical staining1,3 of frozen tissue sections and formalin-fixed paraffin-embedded tissue sections, and Western blotting1. The Ultra-LEAF™ Purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 306221 and 306222).
- Application References
-
- Menashi S, et al. 2003. Cancer Res. 63:7575. (WB IHC)
- Woodhead VE, et al. 2000. Int. Immunol. 12:1051. (Block)
- Reimers N, et al. 2004. Clin. Cancer Res. 10:3422. (IHC)
- Product Citations
-
- RRID
-
AB_314586 (BioLegend Cat. No. 306202)
Antigen Details
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 55-65 kD
- Distribution
-
Leukocytes, erythrocytes, platelets, endothelial cells
- Function
- Adhesion
- Cell Type
- Endothelial cells, Erythrocytes, Leukocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Biswas C, et al. 1995. Cancer Res. 55:434.
2. Fadool J, et al. 1993. Dev. Dyn. 196:252.
3. Felzmann T, et al. 1991. J. Clin. Immunol. 11:205. - Gene ID
- 682 View all products for this Gene ID
- UniProt
- View information about CD147 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD147 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-human CD147 | HIM6 | FC |
Purified anti-human CD147 | HIM6 | FC,IHC-P |
Alexa Fluor® 488 anti-human CD147 | HIM6 | FC,ICC |
Alexa Fluor® 647 anti-human CD147 | HIM6 | FC,ICC,IHC-P |
PE anti-human CD147 | HIM6 | FC |
APC/Fire™ 750 anti-human CD147 | HIM6 | FC |
APC anti-human CD147 | HIM6 | FC |
PE/Cyanine7 anti-human CD147 | HIM6 | FC |
PerCP/Cyanine5.5 anti-human CD147 | HIM6 | FC |
Ultra-LEAF™ Purified anti-human CD147 | HIM6 | FC,WB,IHC,Block |
TotalSeq™-C1137 anti-human CD147 | HIM6 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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FITC anti-human CD147
Human peripheral blood lymphocytes stained with HIM6 FITC -
Purified anti-human CD147
Human peripheral blood lymphocytes stained with purified HIM... Human paraffin-embedded colon tissue slices were prepared wi... Human paraffin-embedded colon tissue slices were prepared wi... -
Alexa Fluor® 488 anti-human CD147
Human peripheral blood lymphocytes stained with HIM6 Alexa F... HeLa cells were fixed with 1% paraformaldehyde (PFA) and the... -
Alexa Fluor® 647 anti-human CD147
Human peripheral blood lymphocytes stained with HIM6 Alexa F... Human paraffin-embedded colon tissue slice was stained with ... HeLa cells were fixed with 1% paraformaldehyde (PFA) and the... -
PE anti-human CD147
Human peripheral blood lymphocytes were stained with CD147 (... -
APC/Fire™ 750 anti-human CD147
Human peripheral blood lymphocytes were stained with CD147 (... -
APC anti-human CD147
Human peripheral blood lymphocytes were stained with CD147 (... -
PE/Cyanine7 anti-human CD147
Human peripheral blood lymphocytes were stained with CD147 (... -
PerCP/Cyanine5.5 anti-human CD147
Human peripheral blood lymphocytes were stained with CD147 (... -
Ultra-LEAF™ Purified anti-human CD147
Human peripheral blood lymphocytes stained with Ultra-LEAF™ ... -
TotalSeq™-C1137 anti-human CD147
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