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Purified anti-human CD82 Antibody

Pricing & Availability
Clone
ASL-24 (See other available formats)
Regulatory Status
RUO
Other Names
KAI1, C33, R2, 4F9, IA4
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
ASL-24_PE_043009.jpg
Human peripheral blood lymphocytes stained with purified ASL-24, followed by anti-mouse IgG PE.
  • ASL-24_PE_043009.jpg
    Human peripheral blood lymphocytes stained with purified ASL-24, followed by anti-mouse IgG PE.
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342102 100 µg 184€
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Description

CD82 is a 45-90 kD type III tetraspan membrane protein which is encoded by the KAI1 gene. A member of the 4-span transmembrane protein superfamily (TM4SF) CD82 forms a complex with CD37, CD53, CD81, ECM and MHC molecules. CD82 is expressed on monocytes, granulocytes, lymphocytes, epithelial cells, endothelial cells, and fibroblasts and plays a role in signal transduction and adhesion. It has been suggested CD82 functions as a tumor suppressor as loss of expression has been found to promote tumor metastasis.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Dutertre CA, et al. 2020. Immunity. 51(3):573-589.e8.. PubMed
RRID
AB_1595421 (BioLegend Cat. No. 342102)

Antigen Details

Structure
Type III tetraspan membrane protein, 45-90 kD, complexed with CD37, CD53, CD81, ECM and MHC molecules, 4-span transmembrane protein superfamily (TM4SF)
Distribution

Monocytes, granulocytes,lymphocytes, epithelial cells, endothelial cells, fibroblasts

Function
Signal transduction, adhesion, tumor metastasis suppressor
Ligand/Receptor
KITENIN
Cell Type
Basophils, Endothelial cells, Epithelial cells, Granulocytes, Lymphocytes, Monocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Miranti CK. 2009. Cell. Signal. 21:196
2. Abe M, et al. 2008. 266:163
3. Lee JH et al. 2004. Cancer Res. 64:4235
4. Lagaudriere-Gesbert C, et al. 1997. J. Immunol. 158:2790

Gene ID
3732 View all products for this Gene ID
UniProt
View information about CD82 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 08/17/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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