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Purified anti-mouse TCR γ/δ Recombinant Antibody

Pricing & Availability
Clone
QA20A46 (See other available formats)
Regulatory Status
RUO
Other Names
TCR-γ/δ, γ/δ TCR
Isotype
Armenian Hamster IgG
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Product Citations
publications
QA20A46_PURE_TCRGammaDelta_Antibody_040522
C57BL/6 mouse splenocytes were stained with purified anti-mouse TCR γ/δ recombinant (clone QA20A46) (left) or purified Armenian hamster IgG isotype control (right) followed by Biotin goat anti-hamster (Armenian) IgG and PE Streptavidin. Cells were costained with anti-mouse CD3 APC.
  • QA20A46_PURE_TCRGammaDelta_Antibody_040522
    C57BL/6 mouse splenocytes were stained with purified anti-mouse TCR γ/δ recombinant (clone QA20A46) (left) or purified Armenian hamster IgG isotype control (right) followed by Biotin goat anti-hamster (Armenian) IgG and PE Streptavidin. Cells were costained with anti-mouse CD3 APC.
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111202 100 µg 85€
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Description

Gamma-delta (γ/δ) T Cells express γ/δ TCR complex. TCR γ/δ associates with CD3 to recognize certain bacterial and tumor antigens. Most TCR γ/δ are CD4-/CD8- while some are CD8+ and are found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. γ/δ T cells have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Recombinant
Host Species
Armenian Hamster
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 50 mM citrate and stabilizer
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone QA20A46 can completely block the binding of clone UC7-13D5 on target cells.

RRID
AB_2924450 (BioLegend Cat. No. 111202)

Antigen Details

Structure
Ig superfamily
Distribution

Subset of T cells

Function
Antigen recognition
Interaction
Associated with CD3 complex
Ligand/Receptor
MHC class I, MHC class I like molecules
Cell Type
Lymphocytes, T cells
Biology Area
Immunology
Molecular Family
TCRs
Antigen References
  1. Skarstein K, et al. 1994. Immunology. 81:497-501.
  2. Harrison LC, et al. 1996. J Exp Med. 184:2167-74.
  3. Wildner G, et al. 1996. Eur J Immunol. 26:2140-8.
  4. Brandes M, et al. 2005. Science. 309:264-8.
  5. Vantourout P, et al. 2013. Nat Rev Immunol. 13:88-100.
Gene ID
110066 View all products for this Gene ID
UniProt
View information about TCR gamma/delta on UniProt.org
Go To Top Version: 1    Revision Date: 04/05/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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