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PE/Cyanine7 anti-human CD155 (PVR) Antibody

Pricing & Availability
Clone
SKII.4 (See other available formats)
Regulatory Status
RUO
Other Names
Poliovirus receptor (PVR), nectin-like 5
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
SKII4_PECy7_CD155_Antibody_FC_052015
U937 cells were stained with CD155 (clone SKII.4) PE/Cyanine7 (filled histogram) or mouse IgG1, κ PE/Cyanine7 isotype control (open histogram).
  • SKII4_PECy7_CD155_Antibody_FC_052015
    U937 cells were stained with CD155 (clone SKII.4) PE/Cyanine7 (filled histogram) or mouse IgG1, κ PE/Cyanine7 isotype control (open histogram).
Compare all formats See PE/Cyanine7 spectral data
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337613 25 tests 137€
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337614 100 tests 306€
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Description

CD155, known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. It is a nectin-like molecule belonging to Ig superfamily. CD155 is primarily found on endothelial cells, monocytes, epithelia and central nervous system. CD155 is an adhesion molecule involved in cell-cell and cell-matrix adhesion through interaction with CD226, CD96 (Tactile), nectin-1, -2, and -3 (CD111, CD112, CD113), and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
SK-N-S1 human neuroblastoma cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: block binding of PVR ligands CD226 and CD96 to PVR, immunoprecipitation, and western blot.

Application References
  1. Fuchs A, et al. 2004. J. Immunol. 172:3994
Product Citations
  1. Rahim MMA, et al. 2020. J Virol. 94:00:00. PubMed
  2. Asashima H, et al. 2022. J Clin Invest. 132: . PubMed
  3. Alejandre Gonzalez AG, et al. 2023. Technol Cancer Res Treat. 15330338221150324:22. PubMed
  4. Lawrence M, et al. 2022. Sci Adv. 8:eabj8618. PubMed
RRID
AB_2565746 (BioLegend Cat. No. 337613)
AB_2565746 (BioLegend Cat. No. 337614)

Antigen Details

Structure
Type I glycoprotein, Ig superfamily
Distribution

Monocytes, endothelial cells, epithelia, central nervous system

Function
Cell-cell and cell-matrix adhesion
Ligand/Receptor
CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus
Cell Type
Endothelial cells, Epithelial cells, Monocytes, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors
Antigen References

1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication
2. Bottino PD, et al. 2005. Mol. Immunol. 42:463
3. Tahara-Hanaoka S, et al. 2004. Intl. Immunol. 16:533

Gene ID
5817 View all products for this Gene ID
UniProt
View information about CD155 on UniProt.org
Go To Top Version: 2    Revision Date: 05/29/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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