Purified anti-mouse CD160 Antibody anti-CD160

Clone: 7H1 (See other available formats)
Regulatory Status: RUO
Other Names: BY55, NK1, NK28
Isotype: Rat IgG2a, κ
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Product Citations: publications

Cat #	Size	Price	Save
143002	100 µg	¥37,620

Description

CD160, also known as BY55, is a 27 kD glycoprotein and member of the Ig superfamily. It is anchored to the cell membrane through glycosylphosphatidylinositol (GPI) and forms disulfide-linked multimers. A soluble form of CD160 is secreted by activated CD8⁺ T cells. Expressed by NK, NKT, γ/δ T cells, intestinal intraepithelial T cells and a subset of memory CD8⁺ T cells, CD160 binds both classical and non-classical MHC class I molecules. It is also a ligand for HVEM. CD160 enhances proliferation of activated CD8⁺ T cells and triggers cell cytotoxicity in NK cells.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Soluble His-Tag mouse CD160
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_11150583 (BioLegend Cat. No. 143002)

Antigen Details

Structure: Membrane glycoprotein, member of the Ig superfamily, 27 kD, glycosylphosphatidylinositol (GPI)-anchored, forms disulfide-linked multimers on the cell surface
Distribution: NK, NKT, γ/δT cells, intestinal intraepithelial T cells, subset of memory CD8+ T cells
Function: Enhances proliferation of activated CD8+ T cells, triggers cell cytotoxicity in NK cells
Ligand/Receptor: Classical and non-classical MHC-class I molecules, HVEM
Cell Type: NK cells, NKT cells, T cells
Biology Area: Immunology, Innate Immunity, Costimulatory Molecules
Molecular Family: CD Molecules, MHC Antigens, TCRs
Antigen References: 1. Shui JW, et al. 2011. J. Leukoc. Biol. 89:517.
2. Del Rio ML, et al. 2010. J. Leukoc. Biol. 87:223.
3. Cai G and Freeman GJ. 2009. Immunol. Rev. 229:244.
Gene ID: 54215 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):: CD160
Specificity Alt (DOES NOT SHOW ON TDS):: CD160
App Abbreviation (DOES NOT SHOW ON TDS):: FC
UniProt: View information about CD160 on UniProt.org

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Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All CD160 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CD160	7H1	FC
PE anti-mouse CD160	7H1	FC
PE/Cyanine7 anti-mouse CD160	7H1	FC
PerCP/Cyanine5.5 anti-mouse CD160	7H1	FC
APC anti-mouse CD160	7H1	FC
TotalSeq™-A1006 anti-mouse CD160	7H1	PG
TotalSeq™-C1006 anti-mouse CD160	7H1	PG

Certificate of Analysis

Go To Top Version: 1 Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

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