APC anti-human CD10 Recombinant Antibody, CD10, QA20A62

Clone: QA20A62 (See other available formats)
Regulatory Status: RUO
Other Names: Common acute lymphoblastic leukemia antigen (CALLA), Enkephalinase, Neutral endopeptidase, Neprilysin
Isotype: Mouse IgG1, κ
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Product Citations: publications

QA20A62_APC_CD10_Antibody_1_121223 — Human peripheral blood leucocytes were stained with anti-human CD10 recombinant (clone QA20A62) APC (left) or mouse IgG1, κ APC isotype control (right).

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Cat #	Size	Price	Save
377403	25 tests	¥28,600
377404	100 tests	¥60,500

Description

CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
Application Notes: Clone QA20A62 can block the binding of HI10A to target cells.
RRID: AB_3097353 (BioLegend Cat. No. 377403)
AB_3097353 (BioLegend Cat. No. 377404)

Antigen Details

Structure: Type II transmembrane metalloprotease family, 100 kD
Distribution: B cell precursors, T cell precursors, neutrophils
Function: Zinc-binding metalloproteinase, B cell development
Interaction: Human
Ligand/Receptor: Biologically active peptides including opioid enkephalins, bradykinin, angiotensions I & II
Cell Type: B cells, Neutrophils
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: Shipp M, et al. 1993. Blood 82:1052-70.

Lu B, et al. 1995. J. Exp. Med. 181:2271-5.
Gene ID: 362443 View all products for this Gene ID
UniProt: View information about CD10 on UniProt.org

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All CD10 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human CD10 Recombinant Antibody	QA20A62	FC
APC anti-human CD10 Recombinant Antibody	QA20A62	FC
APC/Cyanine7 anti-human CD10 Recombinant Antibody	QA20A62	FC
PE anti-human CD10 Recombinant Antibody	QA20A62	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 12/12/2023

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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