APC anti-human FcRL6 Antibody, FcRL6, 7B7/FcRL6

Clone: 7B7/FcRL6 (See other available formats)
Regulatory Status: RUO
Other Names: FcRL6, Fc receptor like 6
Isotype: Mouse IgG1, κ
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Product Citations: publications

Human peripheral blood lymphocytes were stained with anti-human CD56 Brilliant Violet 421™ and anti-human FcRL6 (clone 7B7/FcRL6) APC (left) or mouse IgG1, κ isotype control APC (right).

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Cat #	Size	Price	Save
373903	25 tests	¥41,800
373904	100 tests	¥91,080

Description

FcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8⁺ T cells). Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: BW5147 transduced with HA-tagged FcRL6
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
RRID: AB_2876702 (BioLegend Cat. No. 373903)
AB_2876702 (BioLegend Cat. No. 373904)

Antigen Details

Structure: Type I transmembrane glycoprotein, Ig gene superfamily
Distribution: NK, T subset
Cell Type: NK cells, T cells
Biology Area: Immunology
Molecular Family: Fc Receptors
Antigen References: 1. Davis RS. 2007. Annu. Rev. Immunol. 25:525.
2. Wilson TJ, et al. 2007. Blood 109:3786.
3. Schreeder DM, et al. 2008. 38:3159.
Gene ID: 343413 View all products for this Gene ID
UniProt: View information about FcRL6 on UniProt.org

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Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All FcRL6 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human FcRL6	7B7/FcRL6	FC
APC anti-human FcRL6	7B7/FcRL6	FC
PE anti-human FcRL6	7B7/FcRL6	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 09/02/2020

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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