APC anti-human S100A4 Antibody anti-S100A4

Clone: NJ-4F3-D1 (See other available formats)
Regulatory Status: RUO
Other Names: S100 Calcium Binding Protein A4, 42A, 18A2, CAPL, FSP1, MTS1, P9KA, PEL98, Calvasculin, Metastasin, Placental calcium-binding protein
Isotype: Mouse IgG1, κ
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NJdash4F3dashD1_APC_S100A4_Antibody_042116 — Human peripheral blood mononuclear cells were fixed and permeabilized. Cells were then stained with S100A4 APC (clone NJ-4F3-D1) (filled histogram) or mouse IgG1, κ APC isotype control (open histogram). Data shown was gated on the monocyte population.

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Cat #	Size	Price	Save
370005	25 tests	¥35,420
370006	100 tests	¥82,280

Description

S100A4 is a member of the S100 family of calcium-binding proteins that contain two Ca2⁺-binding EF-hand motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. It can be secreted by unknown mechanisms, stimulating a variety of cellular responses, including angiogenesis and neuronal growth. S100A4 has been shown to be a prognostic marker in a number of human cancers. It also has a potential use as a marker for tumor metastasis and disease progression.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: cDNA
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Red Laser (633 nm)
Application Notes: Additional reported applications (for the relevant formats) include: ELISA Detection.
RRID: AB_2616691 (BioLegend Cat. No. 370005)
AB_2616691 (BioLegend Cat. No. 370006)

Antigen Details

Structure: EF-hand motif.
Distribution: Widely expressed; localized in the cytoplasm and/or nucleus of a vast range of cells.
Function: Calcium-binding.
Cell Type: Neutrophils
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Signal Transduction
Molecular Family: Immune Checkpoint Receptors
Antigen References: 1. Schneider M, et al. 2008. J. Mol. Med. 86:507.
2. Donato R, et al. 2013. Curr. Mol. Med. 13:24.
3. Sherbet GV. 2009. Cancer Lett. 280:15.
Gene ID: 6275 View all products for this Gene ID
UniProt: View information about S100A4 on UniProt.org

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Other Formats

View All S100A4 Reagents Request Custom Conjugation

Description	Clone	Applications
PE anti-human S100A4	NJ-4F3-D1	ICFC
Purified anti-human S100A4	NJ-4F3-D1	ICFC,ELISA Detection
FITC anti-human S100A4	NJ-4F3-D1	ICFC
PerCP/Cyanine5.5 anti-human S100A4	NJ-4F3-D1	ICFC
APC anti-human S100A4	NJ-4F3-D1	ICFC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 04/22/2016

For Research Use Only. Not for diagnostic or therapeutic use.

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