APC anti-mouse LIFR Antibody, LIFR, W16163A

Clone: W16163A (See other available formats)
Regulatory Status: RUO
Other Names: Leukemia inhibitory factor receptor alpha, Leukemia inhibitory factor receptor, Lifr, LIFR-a
Isotype: Rat IgG2b, κ
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W16163A_APC_LIFR_Antibody_052322 — C57 mouse bone marrow was stained with anti-mouse Ly-6C FITC and anti-mouse LIFR (clone W16163A) APC or rat IgG2b, κ APC isotype control.

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Cat #	Size	Price	Save
158905	25 µg	¥36,520
158906	100 µg	¥85,140

Description

Leukemia inhibitory factor (LIFR) receptor alpha belongs to the type I cytokine receptor family, combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of LIF, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in theadult and the embryo.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant mouse LIFR
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
Application Notes: W16163A can be used for surface staining of LIFR expressed on mouse splenocytes and bone marrow cells (tested on C57BL/6).
RRID: AB_2922492 (BioLegend Cat. No. 158905)
AB_2922492 (BioLegend Cat. No. 158906)

Antigen Details

Distribution: IFNAR+ pDCs, IFNAR+ lymphocytes, and Ly6C+ lymphocytes. Dim expression by CD11b+ and CD90.2+ lymphocytes.
Ligand/Receptor: LIFR combines with gp130 to form a receptor complex that mediates the action of LIF
Cell Type: Macrophages, Monocytes
Molecular Family: Cytokine/Chemokine Receptors
Antigen References: Wang T, et al. 2019. Mol Med Rep. 19:4719-26.

Cheng L, et al. 1994. Development. 120:3145-3513.

Mikelonis D, et al. 2014. Orphanet Journal of Rare Diseases. 9:34.
Gene ID: 16880 View all products for this Gene ID
UniProt: View information about LIFR on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Description	Clone	Applications

Related Pages & Pathways

Pathways

IL-6 Pathway

Related FAQs

Other Formats

View All LIFR Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse LIFR	W16163A	FC
PE/Cyanine7 anti-mouse LIFR	W16163A	FC
APC anti-mouse LIFR	W16163A	FC
PE anti-mouse LIFR	W16163A	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 05/23/2022

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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