Loading...

APC/Fire™ 750 anti-mouse CD38 Antibody

Pricing & Availability
Clone
S21016F (See other available formats)
Regulatory Status
RUO
Other Names
T10
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
S21016F_APCFire750_CD38_Antibody_082823
C57BL/6 mouse splenocytes were stained with anti-mouse B220 FITC and anti-mouse CD38 (clone S21016F) APC/Fire™ 750 or rat IgG2b, κ APC/Fire™ 750 isotype control.
  • S21016F_APCFire750_CD38_Antibody_082823
    C57BL/6 mouse splenocytes were stained with anti-mouse B220 FITC and anti-mouse CD38 (clone S21016F) APC/Fire™ 750 or rat IgG2b, κ APC/Fire™ 750 isotype control.
Compare all formats See APC/Fire™ 750 spectral data
Cat # Size Price Save
165605 25 µg ¥30,800
165606 100 µg ¥73,700
Description

CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD38 transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone S21016F can completely block the binding of clone “90” on target cells.

RRID
AB_3068269 (BioLegend Cat. No. 165605)
AB_3068269 (BioLegend Cat. No. 165606)

Antigen Details

Structure
ADP-ribosyl hydrolase, 42 kD
Distribution

B cells, NK cells, T cell subset, brain, muscle, kidney

Function
Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Lymphocytes, NK cells, T cells
Biology Area
Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
  2. Shubinsky G, et al. 1997. Immunity. 7:315-24.
  3. Cesano A, et al. 1998. J Immunol. 160:1106-15.
  4. Cockayne DA, et al. 1998. Blood. 92:1324-33.
Gene ID
12494 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org
Go To Top Version: 1    Revision Date: 08/28/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account