- Clone
- W17055E (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TGFRII, TGFR2, TGFR-2, TβRII, TGFbeta-RII, TGF-Beta Receptor Type II, TGF-Beta Receptor Type-2
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Save |
---|---|---|---|
399709 | 25 tests | ¥42,460 | |
399710 | 100 tests | ¥89,540 |
Transforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- TGFbR2 protein (aa 1-243) expressing transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_2936678 (BioLegend Cat. No. 399709)
AB_2936678 (BioLegend Cat. No. 399710)
Antigen Details
- Distribution
-
B cells, T cells, monocytes, and granulocytes.
- Ligand/Receptor
- TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.
- Cell Type
- B cells, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
- Horbelt D, et al. 2010. J Cell Sci. 123:4340-50.
- Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29.
- Numata S, et al. 2008. J Psychiatr Res. 42:425-32.
- Gene ID
- 7048 View all products for this Gene ID
- UniProt
- View information about TGF-beta Receptor II on UniProt.org
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
-
It is lot-specific. On average it ranges between 2-4.
Other Formats
View All TGF-β Receptor II Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human TGF-β Receptor II | W17055E | FC |
PE anti-human TGF-β Receptor II | W17055E | FC |
APC anti-human TGF-β Receptor II | W17055E | FC |
TotalSeq™-D1171 anti-human TGF-β Receptor II | W17055E | PG |
Brilliant Violet™ 421 anti-human TGF-β Receptor II | W17055E | FC |
PE/Dazzle™ 594 anti-human TGF-β Receptor II | W17055E | FC |
PE/Cyanine7 anti-human TGF-β Receptor II | W17055E | FC |
TotalSeq™-A1171 anti-human TGF-β Receptor II | W17055E | PG |
TotalSeq™-C1171 anti-human TGF-β Receptor II | W17055E | PG |
TotalSeq™-B1171 anti-human TGF-β Receptor II | W17055E | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with CD3 FIT... -
PE anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with CD3 FIT... -
APC anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with CD3 APC... -
TotalSeq™-D1171 anti-human TGF-β Receptor II
-
Brilliant Violet™ 421 anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Cyanine7 anti-human TGF-β Receptor II
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-A1171 anti-human TGF-β Receptor II
-
TotalSeq™-C1171 anti-human TGF-β Receptor II
-
TotalSeq™-B1171 anti-human TGF-β Receptor II
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