FITC anti-mouse CD200R OX2R Antibody anti-CD200R

Clone: OX-110 (See other available formats)
Regulatory Status: RUO
Other Names: OX-2R, Orexin Receptor 2 (OX2R), CD200R
Isotype: Rat IgG2a, κ
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Product Citations: publications

C57BL/6 bone marrow cells stained with OX-110 FITC (gated on myeloid cell populated)

Compare all formats See FITC spectral data

Cat #	Size	Price	Save
123909	50 µg	¥20,680
123910	500 µg	¥72,380

Description

CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils but also by other leukocytes including T lymphocytes and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue. Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function. Levels of expression on resting peripheral blood cells are relatively low.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Fusion protein mouse CD200RCD4d3
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
Application Notes: Additional applications (for the relevant formats) include: in vivo studies³. The Ultra-LEAF™ purified antibody is recommended for functional assays.
RRID: AB_2244385 (BioLegend Cat. No. 123909)
AB_2244385 (BioLegend Cat. No. 123910)

Antigen Details

Distribution: Monocytes and neutrophils, T lymphocytes and mast cells
Cell Type: Mast cells, Monocytes, Neutrophils, T cells
Biology Area: Immunology, Inhibitory Molecules
Molecular Family: CD Molecules
Antigen References: 1. Voulgaraki D, et al. 2005. Immunol. 115:337
Gene ID: 57781 View all products for this Gene ID
UniProt: View information about CD200R on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Description	Clone	Applications

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Other Formats

View All CD200R Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CD200R (OX2R)	OX-110	FC
FITC anti-mouse CD200R (OX2R)	OX-110	FC
PE anti-mouse CD200R (OX2R)	OX-110	FC
TotalSeq™-A0807 anti-mouse CD200R (OX2R)	OX-110	PG
APC anti-mouse CD200R (OX2R)	OX-110	FC
TotalSeq™-C0807 anti-mouse CD200R (OX2R)	OX-110	PG
Ultra-LEAF™ Purified anti-mouse CD200R (OX2R)	OX-110	FC,FA
TotalSeq™-B0807 anti-mouse CD200R (OX2R)	OX-110	PG

Certificate of Analysis

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Go To Top Version: 2 Revision Date: 03/01/2013

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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