- Clone
- 5.1H11 (See other available formats)
- Other Names
- Leu-19, NKH1, NCAM-1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
CD56 is a single transmembrane glycoprotein also known as NCAM (neural cell adhesion molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK and NKT cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparan sulfate.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human myotube cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 100 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Walsh FS, et al. 1981. Nature 289:60. (FC)
- Pavlath GK, et al. 1986. J. Cell Biol. 102:124. (FC)
- Pavlath GK, et al. 1989. Nature 337:570. (FC)
- Pulido R, et al. 1988. J. Immunol. 140:3851. (FC)
- Disclaimer
-
GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include:
- Batch-to-batch consistency
- Material traceability
- Documented procedures
- Documented employee training
- Equipment maintenance and monitoring records
- Lot-specific certificates of analysis
- Quality audits per ISO 13485:2016
- QA review of released products
Antigen Details
- Structure
- Ig superfamily, single transmembrane or GPI-anchored glycoprotein
- Distribution
-
NK cells, T subset, neural tissue, some LGL and myeloid leukemias
- Function
- Adhesion
- Ligand/Receptor
- Heparan sulfate
- Antigen References
-
1. Lanier L, et al. 1991. J. Immunol. 146:4421
2. Hemperly J, et al. 1990. J. Mol. Neurosci. 2:71
3. Cremer H, et al. 1994. Nature 367:455. - Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD56 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD56 (NCAM) Reagents Request Custom ConjugationCompare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with Purified CD5... -
APC anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
PerCP/Cyanine5.5 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD16 AP... -
PE anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
PE/Cyanine7 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
APC/Cyanine7 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD16 FITC an... -
PE/Cyanine5 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD56 (clone ... -
Alexa Fluor® 647 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD56 (clone ... -
Alexa Fluor® 488 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Pacific Blue™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Alexa Fluor® 700 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
PerCP anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Brilliant Violet 650™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Brilliant Violet 510™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Brilliant Violet 421™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD56 (clone ... -
Biotin anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with biotiny... -
Brilliant Violet 605™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (C... -
Brilliant Violet 570™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Brilliant Violet 711™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
PE/Dazzle™ 594 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
FITC anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
Brilliant Violet 785™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD56 (clone ... -
Ultra-LEAF™ Purified anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD56 (c... -
APC/Fire™ 750 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD16 PE... -
PE anti-human CD56 (NCAM)
Typical results from human peripheral blood lymphocytes sta... -
APC anti-human CD56 (NCAM)
Typical results from human peripheral blood lymphocytes sta... -
Brilliant Violet 750™ anti-human CD56 (NCAM)
Human peripheral blood lymphocytes stained with CD56 (clone ... -
TotalSeq™-A0047 anti-human CD56 (NCAM)
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TotalSeq™-C0047 anti-human CD56 (NCAM)
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TotalSeq™-B0047 anti-human CD56 (NCAM)
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Spark NIR™ 685 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with CD16 (c... -
KIRAVIA Blue 520™ anti-human CD56 (NCAM)
Human Peripheral blood lymphocytes were stained with CD16 AP... -
GMP PE anti-human CD56 (NCAM)
Typical results from human peripheral blood lymphocytes stai... -
TotalSeq™-D0047 anti-human CD56 (NCAM)
-
GMP APC anti-human CD56 (NCAM)
Typical results from human peripheral blood lymphocytes stai... -
Spark YG™ 593 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with anti-hu... -
Cell-Vive™ GMP Ultra-LEAF™ Purified anti-human CD56 (NCAM) SF
Human peripheral blood lymphocytes were stained with Cell-Vi... -
Spark Red™ 718 anti-human CD56 (NCAM)
Human peripheral blood lymphocytes were stained with anti-hu... -
Cell-Vive™ GMP Ultra-LEAF™ Biotin anti-human CD56 (NCAM) SF
Human peripheral leukocytes were stained with Cell-Vive™ GMP... -
APC/Fire™ 810 anti-human CD56 (NCAM) Antibody
Human peripheral blood lymphocytes were stained with anti-hu...
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