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- Clone
- K152D10 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- G protein-coupled receptor 19 (GPR19), G protein-coupled receptor gpr-nga, GPR-NGA
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human GPR19 transfected CHO cells were stained with GPR19 (clone K152D10) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram) .
GPR19 is a 415 amino acid protein with two potential glycosylation sites and one disulfide bond that belongs to Orphan G-protein-coupled receptors (GPCRs) with unknown ligand. In mice, GPR19 is highly expressed in the nervous system during embryonic development as well as in specific regions of the mouse adult brain, including the olfactory bulb, the hippocampus, the hypothalamic nuclei, and the cerebellum. It shows low levels of expression in the heart, liver, and kidney. In humans, GPR19 has been reported in regions overlapping with the dopamine D2 receptor in the brain and peripheral nervous system. It was also found in human embryonic stem cells. GPR19 gene was reported to be overexpressed with small cell lung cancer and metastatic melanomas.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- N-terminal Peptide
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2561848 (BioLegend Cat. No. 357003)
Antigen Details
- Structure
- 415 amino acids, seven transmembrane domains, two potential glycosylation site, one disulfide bond
- Distribution
-
Brain and peripheral nervous system
- Function
- Involved in early development of the nervous system, embryonic stem cells
- Biology Area
- Immunology
- Molecular Family
- GPCR
- Antigen References
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1. Kastner S, et al. 2012. Mol Cancer RES. 10:1343.
2. Riker AI, et al. 2008. BMC Med Genomics. 28:1.
3. O'Dowd BF, et al. 1996. FEBS Lett. 7:325. - Gene ID
- 2842 View all products for this Gene ID
- UniProt
- View information about GPR19 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All GPR19 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human GPR19 | K152D10 | FC |
| PE anti-human GPR19 | K152D10 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human GPR19
Human GPR19 transfected CHO cells were stained with purified... -
PE anti-human GPR19
Human GPR19 transfected CHO cells were stained with GPR19 (c...
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