PE anti-human Ksp37 (FGFBP2) Antibody

Pricing & Availability
Clone
TDA3 (See other available formats)
Regulatory Status
RUO
Other Names
Killer-specific secretory protein of 37 kD (Ksp37), FGF binding protein 2 (FGFBP2), Fibroblast growth factor binding protein 2
Isotype
Mouse IgG1, κ
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Product Citations
publications
A_TDA3_PE_011310
Human peripheral blood lymphocytes surface stained with CD56 APC then intracellularly stained with TDA3 PE
  • A_TDA3_PE_011310
    Human peripheral blood lymphocytes surface stained with CD56 APC then intracellularly stained with TDA3 PE
  • B_TDA3_PE_011310
    Human peripheral blood lymphocytes surface stained with CD3 FITC and then intracellularly stained with Ksp37 (TDA3) PE
See PE spectral data
Cat # Size Price Save
346603 25 tests ¥32,120
Description

Ksp37 (killer-specific secretory protein of 37 kD), also known as FGFBP2 (FGF binding protein 2), is a 37 kD Th1-specific secretory protein. It is produced by NK cells, γ/δ T cells, a subset of effector CD8 T cells and Th1 cells, and secreted to serum. Most Ksp37 expressing cells coexpress perforin. It suggests that Ksp37 may be involved in an essential process of cytotoxic lymphocyte-mediated immunity. Elevated Ksp37 level in body fluids has been found in asthma and some infectious disease patients.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Ksp37 cDNA and recombinant Ksp37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

This product is sold under license agreement with BML, Inc for research use only.

Application References

(PubMed link indicates BioLegend citation)
  1. Ogawa K, et al. 2001. J. Immunol. 166:6404
  2. Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359
Product Citations
  1. de Andrade LF, et al. 2019. JCI Insight. 4:e133103. PubMed
  2. Yeo L, et al. 2018. J Clin Invest. 128:3460. PubMed
  3. Collins PL et al. 2018. Cell. 176(1-2):348-360 . PubMed
  4. Corrales L, et al. 2012. J Immunol. 189:4674. PubMed
RRID
AB_2103097 (BioLegend Cat. No. 346603)

Antigen Details

Structure
FGF binding protein family, secreted to serum, 37 kD
Distribution

NK cells, γ/δ T cells, subset of effector CD8 T cells and Th1 cells

Cell Type
NK cells, T cells, Th1
Biology Area
Immunology, Innate Immunity
Antigen References

1. Kuepper M, et al. 2005. Clin. Exp. Allergy. 35:643
2. Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359

Gene ID
643236 View all products for this Gene ID
UniProt
View information about Ksp37 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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