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- Clone
- TDA3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Killer-specific secretory protein of 37 kD (Ksp37), FGF binding protein 2 (FGFBP2), Fibroblast growth factor binding protein 2
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes surface stained with CD56 APC then intracellularly stained with TDA3 PE -
Human peripheral blood lymphocytes surface stained with CD3 FITC and then intracellularly stained with Ksp37 (TDA3) PE
Ksp37 (killer-specific secretory protein of 37 kD), also known as FGFBP2 (FGF binding protein 2), is a 37 kD Th1-specific secretory protein. It is produced by NK cells, γ/δ T cells, a subset of effector CD8 T cells and Th1 cells, and secreted to serum. Most Ksp37 expressing cells coexpress perforin. It suggests that Ksp37 may be involved in an essential process of cytotoxic lymphocyte-mediated immunity. Elevated Ksp37 level in body fluids has been found in asthma and some infectious disease patients.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ksp37 cDNA and recombinant Ksp37
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
This product is sold under license agreement with BML, Inc for research use only.
-
Application References
(PubMed link indicates BioLegend citation) -
- Ogawa K, et al. 2001. J. Immunol. 166:6404
- Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359
- Product Citations
-
- RRID
-
AB_2103097 (BioLegend Cat. No. 346603)
Antigen Details
- Structure
- FGF binding protein family, secreted to serum, 37 kD
- Distribution
- NK cells, γ/δ T cells, subset of effector CD8 T cells and Th1 cells
- Cell Type
- NK cells, T cells, Th1
- Biology Area
- Immunology, Innate Immunity
- Antigen References
-
1. Kuepper M, et al. 2005. Clin. Exp. Allergy. 35:643
2. Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359 - Gene ID
- 643236 View all products for this Gene ID
- UniProt
- View information about Ksp37 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All Ksp37 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human Ksp37 (FGFBP2) | TDA3 | ICFC |
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