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- Clone
- HSL2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Pre-B cell Receptor
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Human pre-B cell line Nalm-6 intracellularly stained with HSL2 PE
The human Pre-BCR is composed of mH chain and CD179a (VpreB)/CD179b (λ5). The mAb HSL2 reacts with a conformational epitope unique to the Pre-BCR complex. The Pre-BCR associates with the signal transducing heterodimer, CD79a/CD79b, to form the Pre-BCR complex. Pre-BCR is expressed on Pro-B and early Pre-B cells and plays a critical role in B cell development.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
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Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Tsuganezawa K, et al. 1998. Blood 92:4317.
- Kiyokawa N, et al. 2004. Modern Pathology 17:423.
- RRID
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AB_2063902 (BioLegend Cat. No. 347904)
Antigen Details
- Structure
- Ig superfamily, Pre-BCR is compose of CD179a, CD179b andµH
- Distribution
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Pro-B and early Pre-B cells
- Cell Type
- B cells
- Biology Area
- Immunology
- Antigen References
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1. LeBien TW, et al. 2000. Blood 96:9.
2. Zhang M, et al. 2004. Cell Mol Immunol. 1:89. - Gene ID
- 613 View all products for this Gene ID
- UniProt
- View information about Pre-BCR on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All Pre-BCR Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human Pre-BCR | HSL2 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human Pre-BCR
Human pre-B cell line Nalm-6 intracellularly stained with HS...
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