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- Clone
- S20010A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Tetraspanin-8
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human colon cancer cell line, HT-29, was stained with anti-human TSPAN8 (clone S20010A) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
| Cat # | Size | Price | Save |
|---|---|---|---|
| 378903 | 25 tests | ¥35,200 | |
| 378904 | 100 tests | ¥79,200 |
Tetraspanin 8 (TSPAN8) is a member of the transmembrane IV superfamily. It is a cell surface protein with four hydrophobic domains. Tetraspanins are constitutive components of exosomes and are involved in adhesion, motility, matrix modulation and cell fusion. TSPAN8 mediates signal transduction events that regulate cell development, activation, growth, and motility. It is expressed in gastric, colon, rectal, and pancreatic carcinomas.
Product Details
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- huTSPAN8 transfectant
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
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Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2941553 (BioLegend Cat. No. 378903)
AB_2941553 (BioLegend Cat. No. 378904)
Antigen Details
- Structure
- Multi-pass membrane protein
- Distribution
-
Cell membrane, lysosomes
- Function
- Tyrosine-based internalization, recruitment into endosomes
- Interaction
- LIPR1, MEP1B, STX1-2, TIM23, S38A7
- Biology Area
- Immunology
- Antigen References
-
- Szala S, et al. 1990. Proc Natl Acad Sci USA. 87:6833-7.
- Rana S, et al. 2011. Int J Biochem Cell Biol. 43:106-19.
- Nazarenko I, et al. 2010. Cancer Res. 70:1668-78.
- Berthier-Vergnes O, et al. 2011. Br J Cancer. 104:155-68.
- Gene ID
- 7103 View all products for this Gene ID
- UniProt
- View information about TSPAN8 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All TSPAN8 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human TSPAN8 | S20010A | FC,IHC-P |
| PE anti-human TSPAN8 | S20010A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human TSPAN8
Human colon cancer cell line, HT-29, was stained with purifi... 
Human paraffin embedded colon tissue was subjected to heat-m... -
PE anti-human TSPAN8
Human colon cancer cell line, HT-29, was stained with anti-h...
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