PE anti-mouse DLL3 Antibody

Pricing & Availability
Clone
RMD3-13 (See other available formats)
Regulatory Status
RUO
Other Names
Delta like 3, M-Delta-3, delta3, drosophila Delta homolog 3
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
RMD3-13_PE_DLL3_Antibody_042618
Mouse DLL3 transfected OP9 cells were fixed, permeabilized and intracellularly stained with DLL3 (clone RMD3-13, solid histogram) PE or rat IgG2b, κ PE isotype control (open histogram).
  • RMD3-13_PE_DLL3_Antibody_042618
    Mouse DLL3 transfected OP9 cells were fixed, permeabilized and intracellularly stained with DLL3 (clone RMD3-13, solid histogram) PE or rat IgG2b, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Save
154003 25 µg ¥31,020
154004 100 µg ¥76,340
Description

Delta like canonical Notch ligand 3 (DLL3) is consist of a DSL domain, EGF  repeats and transmembrane region. Inhibits Notch 1 in its cis format. Involved in embryonic development processes such as T cells development, specifying neuron's fate during neurogenesis and maintaining tissue homeostasis in adults. Potential target for preventing growth of cancer cells in small cell lung cancer.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse DLL3-FC
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Murata A, et al. 2014. PLoS One. 9:e108535.
Product Citations
  1. Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
RRID
AB_2734227 (BioLegend Cat. No. 154003)
AB_2734227 (BioLegend Cat. No. 154004)

Antigen Details

Structure
Type I transmembrane protein with a DSL domain and 6 or 8 EGF-like repeats
Distribution

Thymus, Brain

Function
Embryogenesis, maintaining tissue homeostasis
Interaction
Inhibition of Notch downstream signaling
Ligand/Receptor
Notch 1
Biology Area
Immunology
Molecular Family
Adhesion Molecules
Antigen References

1. Deng S M, et al. 2017. Biochem Biophys Res Commun. 483:488.
2. Shapiro F. 2016. Adv. Anat. Embryol. Cell. Biol. 221:67.
3. Saunders LR, et al. 2015. Sci Transl Med. 7:302.
4. Dvoriantchikova G, et al. 2015. PLoS One. 10:e0131054. 

Gene ID
13389 View all products for this Gene ID
UniProt
View information about DLL3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 05/01/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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