- Clone
- QA20A56 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- PLCG2, APLAID, FCAS3, PLC-IV
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
PLCγ2 is a member of the PLC family. PLCγ is the only member that contains SH2 and SH3 domains, which enable it to interact with protein tyrosine kinases and become activated by phosphorylation. PLCγ2 is expressed primarily on hematopoietic stem cells and on B cells. PLCγ2 catalyzes the hydrolysis of phospholipids to yield second messenger molecules diacylglycerol (DAG) and inositol triphosphate (IP3).
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2922612 (BioLegend Cat. No. 380903)
Antigen Details
- Distribution
-
B cells
- Function
- Cell signaling
- Antigen References
-
- Kurosaki T, et al. 2000. Immunol Rev. 176:19-29.
- Noh DY, et al. 1995, Biochim Biophys Acta. 1242:99-113.
- Kang JS, et al. 1996, FEBS Lett. 399:14-20.
- Gene ID
- 5336 View all products for this Gene ID
- UniProt
- View information about PLCgamma2 Phospho Tyr759 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All PLCγ2 Phospho Tyr759 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-PLCγ2 Phospho (Tyr759) Recombinant Antibody | QA20A56 | ICFC |
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PE anti-PLCγ2 Phospho (Tyr759) Recombinant Antibody
Ramos cells (a Burkitts Lymphoma cell line) were treated wit...
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