- Clone
- QA17A16 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Leu-19, NKH1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Fire™ 810 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Fire™ 810 has a maximum excitation of 488/561 nm and a maximum emission of 810 nm.
Excessive exposure to light, and commonly used fixation, permeabilization buffers can affect PE/Fire™ 810 fluorescence signal intensity and spread. Please keep conjugates protected from light exposure. For more information and representative data, visit our Fire Dyes page. - Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2927902 (BioLegend Cat. No. 392435)
Antigen Details
- Structure
- Ig superfamily, single transmembrane or GPI-anchored glycoprotein
- Distribution
-
NK cells, NK-Tcells, brain and neuromuscular junctions, certain large granular lymphocyte (LGL) leukemias, small-cell lung carinomas, neuronal derived tumors, myelomas, and myeloid leukemias
- Function
- Adhesion
- Ligand/Receptor
- Heparin sulfate
- Cell Type
- Leukemia, Neurons, NK cells, NKT cells
- Biology Area
- Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Lanier L, et al. 1991. J. Immunol. 146:4421.
2. Hemperly J, et al. 1990. J. Mol. Neurosci. 2:71.
3. Cremer H, et al. 1994. Nature 367:455. - Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD56 on UniProt.org
Other Formats
View All CD56 Reagents Request Custom ConjugationCustomers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with purifie... -
PE anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were satined with APC CD3... -
APC anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 FIT... -
Alexa Fluor® 700 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 FIT... -
APC/Fire™ 750 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were satined with FITC CD... -
PE/Dazzle™ 594 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were satined with FITC CD... -
FITC anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 Per... -
PE/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with FITC CD... -
Pacific Blue™ anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 Per... -
TotalSeq™-A0084 anti-human CD56 (NCAM) Recombinant Antibody
-
PerCP/Cyanine5.5 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 FIT... -
TotalSeq™-B0084 anti-human CD56 (NCAM) Recombinant Antibody
-
TotalSeq™-C0084 anti-human CD56 (NCAM) Recombinant Antibody
-
PE/Fire™ 700 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
Spark YG™ 581 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 640 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD3 APC... -
PE anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
APC/Fire™ 750 anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
APC anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
FITC anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
PerCP/Cyanine5.5 anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
PE/Cyanine7 anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
Pacific Blue™ anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
PE/Dazzle™ 594 anti-human CD56
Typical results from human peripheral blood lymphocytes stai... -
Spark Red™ 718 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 810 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
Spark PLUS UV395™ anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu...
Follow Us