PerCP/Cyanine5.5 anti-human TCR Vα24 Antibody

Pricing & Availability
Clone
C15/TCR Vα24 (See other available formats)
Regulatory Status
RUO
Other Names
TCRAV24S1, TCRAV10
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
C15-TCRVa24_PerCpCyanine55_TCRVa24 _Antibody_083018
Peripheral blood lymphocytes were stained with CD3 APC and TCR Va24 (Clone C15/ TCR Va24) PerCP/Cyanine5.5 (left), or mouse IgG1, κ PerCP/Cyanine5.5 isotype control (right).
  • C15-TCRVa24_PerCpCyanine55_TCRVa24 _Antibody_083018
    Peripheral blood lymphocytes were stained with CD3 APC and TCR Va24 (Clone C15/ TCR Va24) PerCP/Cyanine5.5 (left), or mouse IgG1, κ PerCP/Cyanine5.5 isotype control (right).
See PerCP/Cyanine5.5 spectral data
Cat # Size Price Save
360004 100 tests ¥84,040
This product is scheduled for discontinuation. Please use the availability checker to determine current availability.
Description

TCR Vα24 is a highly variable region on the TCR which functions in antigen recognition through MHC molecules. TCR Vα24 has been shown to be expressed on a subset of peripheral blood CD3+ lymphocytes. It is also expressed on a population of CD3+CD4-CD8- T cells (invariant NKT cells or iNKT) that produce large amounts of cytokines following stimulation. TCR Vα24 expressing iNKT cells have been reported to be important in immune responses to self and foreign antigens.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human T-cell clone
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Product Citations
  1. Lao L, et al. 2023. Cancer Immunol Res. 11:320. PubMed
  2. Jimeno R, et al. 2019. Elife. :8. PubMed
RRID
AB_2562495 (BioLegend Cat. No. 360004)

Antigen Details

Structure
Disulfide-linked 80 kD heterodimer consisting of an α and β chain
Distribution

CD+ invariant NKT cells (iNKT), subset of CD3+ T cells

Function
Recognize antigens bound to MHC molecules
Ligand/Receptor
Antigen bound MHC molecules
Cell Type
NKT cells, T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Koop BF, et al. 1994. Genomics. 19:478.
2. Kent SC, et al. 1999. Hum. Immunol. 60:1080.
3. Capone M, et al. 2003. J. Immunol. 170:2390.

Gene ID
28659 View all products for this Gene ID
UniProt
View information about TCR Valpha24 on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Go To Top Version: 2    Revision Date: 08/30/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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