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- Clone
- 74/3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Lipocortin-1, p35, annexin-1, calpactin-2, calpactin II, lipocortin I, chromobindin-9, annexin I (lipocortin I), phospholipase A2 inhibitory protein
- Previously
-
Covance Catalog# MMS-5237
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Lipocortin-1 (74/3) and isotype control staining of K562 cells analyzed by flow cytometry. Cells were pretreated with Fix/Perm buffer. A goat anti-mouse-PE conjugate was used as secondary antibody.
Annexin1 (also known as Lipocortin-1) is a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. Phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins, and leukotrienes. Lipocortin-1 has phospholipase A2 inhibitory activity, thus therefore it is an anti-inflammatory protein.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against AG1523 human fibroblast cells.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_2564948 (BioLegend Cat. No. 831601)
Antigen Details
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience
- Molecular Family
- Phospho-Proteins
- Gene ID
- 301 View all products for this Gene ID
- UniProt
- View information about Annexin A1 on UniProt.org
Other Formats
View All Annexin A1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-Annexin A1 | 74/3 | FC |
| APC anti-Annexin A1 | 74/3 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-Annexin A1
Lipocortin-1 (74/3) and isotype control staining of K562 cel... -
APC anti-Annexin A1
Jurkat cells were treated with 5 µM Camptothecin for 4 hours... 
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