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Purified anti-CCL11 Antibody

Pricing & Availability
Clone
L403H11 (See other available formats)
Regulatory Status
RUO
Other Names
Eotaxin, eotaxin-1, small inducible cytokine subfamily A, member 11 (SCYA11)
Isotype
Rat IgG1, κ
Ave. Rating
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Product Citations
publications
L403H11_PURE_CCL11_ELISA_Antibody_122016
  • L403H11_PURE_CCL11_ELISA_Antibody_122016
Cat # Size Price Save
683202 500 µg ¥64,460
Description

CCL11 is a member of the CC chemokine family. It was originally identified as a chemoattractant for eosinophils, and participates in a variety of allergic responses to allergens. CCL11 induces angiogenic responses in CCR3+ microvascular endothelial cells and facilitates the proliferation and metastasis of CCR3+ tumor cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant Mouse CCL11, (amino acids (His24-Pro97, Accession# NM_011330), were expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by ELISA. For ELISA capture applications, a concentration of 0.5 µg/mL is recommended. To obtain a linear standard curve, serial dilutions of CCL11 recombinant protein ranging from 500 to 7.81 pg/mL are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance.

RRID
AB_2686953 (BioLegend Cat. No. 683202)

Antigen Details

Structure
Chemokine
Distribution

Epithelial cells, smooth muscle cells, dendritic cells, fibroblasts, mast cells, and Th2 lymphocytes.

Function
Recruits eosinophils in allergic responses. Stimulates eosinophil release from bone marrow, increasing levels of circulating eosinophils. Induced by pro-inflammatory cytokines (IL-4, IL-13, TNF-7alpha;, and IFN-α).
Interaction
Eosinophils
Ligand/Receptor
CCR3
Cell Type
Epithelial cells, Dendritic cells, Fibroblasts, Mast cells, Th2, Eosinophils
Biology Area
Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
Cytokines/Chemokines
Antigen References

1. Crump MP, et al. 1998. J. Biol. Chem. 273:22471.
2. Conroy DM, et al. 2001. Respir. Res. 2:150.
3. Salcedo R, et al. 2001. J. Immunol. 166:7571.
4. Hadjicharalambous C, et al. 2004. J. Allergy Clin. Immunol. 113:657.
5. Kaehler J, et al. 2006. J. Investig. Med. 54:446.
6. Levina V, et al. 2009. Clin. Cancer Res. 15:2647.

Gene ID
20292 View all products for this Gene ID
UniProt
View information about CCL11 on UniProt.org

Other Formats

View All CCL11 Reagents Request Custom Conjugation
Description Clone Applications
Ultra-LEAF™ Purified anti-CCL11 L403H11 Block,ELISA Capture,Neut
Purified anti-CCL11 L403H11 ELISA Capture
Go To Top Version: 0    Revision Date: 04/06/2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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