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- Clone
- S22003B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Syndecan-1, B-B4
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human myeloma cell line U266 was stained with purified anti-human CD138 (Syndecan-1) (clone S22003B) (filled histogram) or purified rat IgG2a, κ isotype control (open histogram).
CD138, also known as Syndecan-1, is a type I integral membrane heparin sulfate proteoglycan. As a member of the syndecan protein family, Syndecan-1 mediates multiple cellular processes, including migration, proliferation, and cell-matrix adhesion through interactions with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant human syndecan-1 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Clone S22003B does not affect the binding of clones MI15, DL-101, S22003D, and S22003F on target cells.
Binding of clone S22003B on fixed target cells is not significantly reduced compared to un-fixed cells. - RRID
-
AB_3106064 (BioLegend Cat. No. 390002)
Antigen Details
- Structure
- 100-200 kD type I transmembrane glycoprotein
- Distribution
-
Plasma cells, pre-B cells, epithelial cells, endothelial cells
- Function
- Adhesion, controls cell morphology, regulates cell growth
- Ligand/Receptor
- FGFb, collagen, fibronectin
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Plasma cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Sanderson RD, et al. 1992. Cell Regul. 1:27.
- Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers. Wiley-Liss A John Wiley & Sons Inc, Publication.
- Gene ID
- 6382 View all products for this Gene ID
- UniProt
- View information about CD138 on UniProt.org
Related FAQs
Other Formats
View All CD138 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD138 (Syndecan-1) | S22003B | FC |
| PE anti-human CD138 (Syndecan-1) | S22003B | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with purified anti-... -
PE anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with anti-human CD1...
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