- Clone
- A18042B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- OX-2, OX2
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![A18042_PURE_CD200_Antibody_050820 A18042_PURE_CD200_Antibody_050820](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/A18042_PURE_CD200_Antibody_050820.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with purified anti-human CD200 (OX2) (clone A18042B) (left) or mouse IgG1, κ isotype control (right), followed by anti-mouse IgG PE. Cells were Co-stained with CD4 APC.
CD200, also known as OX2, is a member of the immunoglobulin superfamily (IgSF). It is a monomorphic cell surface glycoprotein that is expressed on thymocytes, neurons, endothelium, follicular dendritic cells in all lymphoid organs, a subset of CD34+ progenitor cells, and at low levels on some smooth muscle and B lymphocytes. It is not expressed on NK cells, monocytes, granulocytes, or platelets. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. The interaction between CD200 (OX2) and CD200 receptor (OX2R) system is of importance in the control of macrophage and granulocyte activation, which may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD200
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Clone A18042B antibody is able to completely block the staining of OX-104 antibody, but OX-104 antibody does not completely block the staining of A18042B antibody.
- RRID
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AB_2861014 (BioLegend Cat. No. 399802)
Antigen Details
- Structure
- Ig superfamily, 80 kD
- Distribution
-
T cells, neurons, endothelium
- Function
- Costimulates T cell proliferation
- Ligand/Receptor
- CD200R
- Cell Type
- Endothelial cells, Neurons, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
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- Wright GJ, et al. 2001. Immunology. 102:173.
- Foster-Cuevas M, et al. 2004. J. Virol. 78:7667.
- Mason D, et al. 2002. ed. Leukocyte Typing VII. New York:Oxford Univ. Press.
- Broderick C, et al. 2002. Am. J. Pathol. 161:1669.
- Gene ID
- 4345 View all products for this Gene ID
- UniProt
- View information about CD200 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD200 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD200 (OX2) | A18042B | FC |
Purified anti-human CD200 (OX2) | A18042B | FC |
PE/Cyanine7 anti-human CD200 (OX2) Antibody | A18042B | FC |
APC anti-human CD200 (OX2) | A18042B | FC |
TotalSeq™-D1278 anti-human CD200 (OX2) | A18042B | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD200 (OX2)
Human peripheral blood lymphocytes were stained with APC CD4... -
Purified anti-human CD200 (OX2)
Human peripheral blood lymphocytes were stained with purifie... -
PE/Cyanine7 anti-human CD200 (OX2) Antibody
Human peripheral blood lymphocytes were stained with CD4 APC... -
APC anti-human CD200 (OX2)
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-D1278 anti-human CD200 (OX2)
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